Indications
Lanthanum Carbonate is a phosphate binder. Doctors use it to lower the level of phosphate in the blood (serum phosphate) in patients with end-stage renal disease (ESRD).
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Lanthanum Carbonate is a phosphate binder. It forms insoluble Lanthanum phosphate complexes that pass through the Gl tract without being absorbed, so less phosphate gets into the body. Because less dietary phosphate is absorbed, both serum phosphate and calcium phosphate product go down.
In vitro studies show that Lanthanum binds phosphate across the physiologically relevant pH range of 3 to 7. In simulated gastric fluid, when Lanthanum is present in a two-fold molar excess to phosphate, it binds approximately 97% of the available phosphate at pH 3-5 and 67% at pH 7. Bile acids have not been shown to affect how well Lanthanum binds phosphate.
To bind dietary phosphate, Lanthanum Carbonate must be taken with meals or immediately after them.
Pregnancy & Breastfeeding
Pregnancy: The case reports available on Lanthanum Carbonate in pregnant women don't give enough information to say whether the medicine carries a risk of major birth defects, miscarriage, or other harmful outcomes for the mother or the baby. In a pregnant woman, use a phosphate binder that does not contain Lanthanum.
Lactation: There are no data on whether Lanthanum Carbonate passes into human milk, what effect it has on a breastfed infant, or whether it changes milk production. In a woman who is breastfeeding, use a phosphate binder that does not contain Lanthanum.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.