Lamivudine [For Chronic Hepatitis B]
Indications
Lamivudine [For Chronic Hepatitis B] is used to treat chronic hepatitis B in people who show signs that the hepatitis B virus is multiplying and who also have active inflammation in the liver.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Lamivudine is a synthetic nucleoside analogue. Inside the cell it is phosphorylated to lamivudine triphosphate. The monophosphate form is then built into viral DNA by hepatitis B virus (HBV) polymerase, and this ends the DNA chain. Lamivudine triphosphate also inhibits the RNA and DNA-dependent DNA polymerase activities of HIV-1 reverse transcriptase (RT). It is only a very weak inhibitor of mammalian alpha, beta and gamma-DNA polymerases.
Pregnancy & Breastfeeding
No adequate and well-controlled study has been done in pregnant women, so Lamivudine should be used in pregnancy only if the expected benefit is greater than the risk. It isn't known whether lamivudine passes into human milk. Because it could cause adverse effects in a nursing infant, mothers who are receiving lamivudine should be told not to breastfeed.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.