Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Insulin Human [rDNA] Injection is used in the treatment of all patients with type 1 diabetes. It is also used in the treatment of patients with type 2 diabetes who are not adequately controlled by diet and/or oral hypoglycemic agents. Doctors use it for the initial stabilization of diabetes in patients with diabetic ketoacidosis or hyperosmolar non-ketotic syndrome, and during periods of stress such as severe infections and major surgery in diabetic patients. It is also used in the treatment of gestational diabetes.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Insulin Human is a sterile, clear, colourless solution. It is a fast-acting insulin, and its action lasts a relatively short time compared with other insulins. It may be used together with long-acting insulins.

Insulin lowers blood glucose because it binds to receptors on muscle and fat cells, which helps these cells take up glucose. At the same time, it stops the liver from releasing glucose.

In the blood stream, insulin has a half-life of a few minutes. It does not bind profoundly to plasma proteins.

After a subcutaneous injection, the average action profile is as follows:

Onset of action: within 30 minutes

Peak plasma levels: reached between 1 to 3 hours

Duration of action: approximately 4 to 6 hours

Pregnancy & Breastfeeding

Insulin Human [rDNA] can be used to treat diabetes during pregnancy without any restriction, because insulin doesn't cross the placental barrier. Poorly controlled diabetes is the real danger. Both hypoglycaemia and hyperglycaemia can happen when diabetes therapy isn't adequate, and either one raises the risk of malformations and death in utero.

Insulin requirements usually fall in the first trimester. They then rise through the second and third trimesters. After delivery, the requirement goes back quickly to what it was before pregnancy.

A nursing mother can take insulin without any risk to her baby. Her insulin dosage, her diet or both may still need to be adjusted.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Dosage is individual, and the physician decides it according to the needs of the patient. For maintenance therapy in type 1 diabetic patients, the average total daily insulin requirement lies between 0.5 and 1.0 IU/Kg. In pre-pubertal children it usually varies from 0.7 to 1.0 IU/Kg. The daily insulin requirement may be higher in patients with insulin resistance (for example during puberty in the young, or due to obesity). It may be lower in patients with endogenous insulin production, or during a period of partial remission. The initial dosage for type 2 diabetic patients is often lower, for example 0.3 to 0.6 IU/Kg/Day. An injection should be followed within 30 minutes by a meal or snack containing carbohydrates.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.