Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Insulin Aspart + Insulin Aspart Protamine is a mixture of Insulin Aspart and Insulin Aspart Protamine. Doctors use it to improve glycemic control in patients with diabetes mellitus.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Insulin Aspart & Insulin Aspart Protamine is a human insulin analog suspension that contains 30% Insulin Aspart and 70% Insulin Aspart Protamine, and it is used to lower blood glucose. Insulin Aspart is homologous with regular human insulin, except for a single substitution of the Amino Acid Proline by Aspartic Acid in position B28. It is produced by recombinant DNA technology, using Saccharomyces cerevisiae (baker's yeast). The main activity of insulin, Insulin Aspart included, is the regulation of glucose metabolism. Insulin and its analogs lower blood glucose by stimulating peripheral glucose uptake, especially by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulin also inhibits lipolysis and proteolysis, and it increases protein synthesis.

Pregnancy & Breastfeeding

Insulin Aspart + Insulin Aspart Protamine is listed as pregnancy category B. No data are available from pregnant women, so a risk linked to the medicine itself can't be worked out. Poorly controlled diabetes during pregnancy does carry risks for both the mother and the baby. For breastfeeding, there are no data on whether insulin passes into human milk, what effect it has on a breastfed infant, or whether it changes milk production.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Insulin Aspart + Insulin Aspart Protamine is usually given twice a day, and each dose is meant to cover 2 meals, or a meal and a snack. The dose is set for the individual patient, based on their metabolic needs, their blood glucose monitoring results and their glycemic control goal. The dose may need adjusting when physical activity changes, when meal patterns change, when kidney or liver function changes, or during an acute illness. It may also need adjusting when a patient switches from another insulin to this one. Or the dose can follow whatever the registered physician directs. Blood glucose should be monitored in every patient treated with insulin. Any change to an insulin regimen should be made cautiously and only under medical supervision. Renal and Hepatic Impairment: the dose may need to be reduced in these cases.

Side Effects & Interactions