Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
RapiMix is indicated for:
Pharmacology
Insulin Aspart & Insulin Aspart Protamine is a human insulin analog suspension that contains 30% Insulin Aspart and 70% Insulin Aspart Protamine, and it is used to lower blood glucose. Insulin Aspart is homologous with regular human insulin, except for a single substitution of the Amino Acid Proline by Aspartic Acid in position B28. It is produced by recombinant DNA technology, using Saccharomyces cerevisiae (baker's yeast). The main activity of insulin, Insulin Aspart included, is the regulation of glucose metabolism. Insulin and its analogs lower blood glucose by stimulating peripheral glucose uptake, especially by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulin also inhibits lipolysis and proteolysis, and it increases protein synthesis.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Insulin Aspart + Insulin Aspart Protamine is usually given twice a day, and each dose is meant to cover 2 meals, or a meal and a snack. The dose is set for the individual patient, based on their metabolic needs, their blood glucose monitoring results and their glycemic control goal.
The dose may need adjusting when physical activity changes, when meal patterns change, when kidney or liver function changes, or during an acute illness. It may also need adjusting when a patient switches from another insulin to this one. Or the dose can follow whatever the registered physician directs.
Blood glucose should be monitored in every patient treated with insulin. Any change to an insulin regimen should be made cautiously and only under medical supervision.
Renal and Hepatic Impairment: the dose may need to be reduced in these cases.
Side Effects
The side effects seen most often with Insulin Aspart + Insulin Aspart Protamine are hypoglycemia, hypersensitivity and allergic reactions, hypokalemia, injection site reaction, lipodystrophy, pruritus and rash.
Cautions & Contraindications
Contraindications
Don't use Insulin Aspart while a person is having a hypoglycemic episode. It also must not be given to anyone who is hypersensitive to the medicine or to any of its excipients.
Pregnancy & Breastfeeding
Insulin Aspart + Insulin Aspart Protamine is listed as pregnancy category B. No data are available from pregnant women, so a risk linked to the medicine itself can't be worked out. Poorly controlled diabetes during pregnancy does carry risks for both the mother and the baby. For breastfeeding, there are no data on whether insulin passes into human milk, what effect it has on a breastfed infant, or whether it changes milk production.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Too much insulin, such as an overdose of Insulin Aspart + Insulin Aspart Protamine, can cause hypoglycemia. When the insulin is given intravenously, it can also cause hypokalemia. A mild episode of hypoglycemia can usually be treated with oral glucose. The dose of the medicine, the pattern of meals or the amount of exercise may need to be adjusted. Hypokalemia must be corrected appropriately.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Storage when not in use: keep the Insulin Aspart + Insulin Aspart Protamine in a refrigerator (2°C to 8°C) and don't freeze it. When you take it out of the refrigerator, it is recommended to let it reach room temperature before you resuspend the insulin for the first time.
Storage during use: the insulin that is in use should not be kept in the refrigerator. You can keep it at room temperature (below 30°C) for up to 4 weeks. Leave the cartridge in its outer carton to protect it from light, and keep it away from excessive heat and light.
Drug Interactions
Common questions about RapiMix 30%+70%
What is RapiMix 30%+70% SC Injection?
RapiMix 30%+70% SC Injection is a medicine that contains Insulin Aspart + Insulin Aspart Protamine. It is made by Square Pharmaceuticals PLC, Pabna. It belongs to the Rapid Acting Insulin group of medicines.
What is RapiMix used for?
RapiMix is used for: Diabetes Mellitus.
What are the side effects of RapiMix?
The side effects seen most often with Insulin Aspart + Insulin Aspart Protamine are hypoglycemia, hypersensitivity and allergic reactions, hypokalemia, injection site reaction, lipodystrophy, pruritus and rash.
Can I take RapiMix during pregnancy or while breastfeeding?
Insulin Aspart + Insulin Aspart Protamine is listed as pregnancy category B. No data are available from pregnant women, so a risk linked to the medicine itself can't be worked out. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much RapiMix?
Too much insulin, such as an overdose of Insulin Aspart + Insulin Aspart Protamine, can cause hypoglycemia. When the insulin is given intravenously, it can also cause hypokalemia. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store RapiMix?
Storage when not in use: keep the Insulin Aspart + Insulin Aspart Protamine in a refrigerator (2°C to 8°C) and don't freeze it. When you take it out of the refrigerator, it is recommended to let it reach room temperature before you resuspend the insulin for the first time.
Can I take other medicines with RapiMix?
Some medicines can interact with Insulin Aspart + Insulin Aspart Protamine, for example: Niacin, Isoniazid, Disopyramide, Somatropin, Pentoxifylline, Danazol. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for RapiMix?
RapiMix is a prescription (Rx) medicine. Take it as your doctor advises.