Informational only — Not medical advice. Always consult a licensed healthcare provider.

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Community data Updated 23 hours ago
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Indications

Rheumatoid Arthritis

Iguratimod tablet is used to treat rheumatoid arthritis (RA), a common autoimmune disease. It belongs to the group called conventional synthetic disease-modifying antirheumatic drugs (csDMARDs). Iguratimod has also shown promise in other rheumatic and autoimmune conditions, including Sjögren's syndrome, ankylosing spondylitis and systemic lupus erythematosus (SLE).

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Iguratimod has immunomodulatory effects, because it acts on both T and B lymphocytes to suppress the immune response. Its anti-inflammatory action comes from inhibiting the production of pro-inflammatory cytokines such as TNF-α, IL-1β, IL-6 and IL-17, which contribute to inflammation. It also has an osteoprotective activity. Iguratimod promotes bone formation while inhibiting the differentiation and activity of osteoclasts, the cells that resorb bone.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: For rheumatoid arthritis, the usual adult dose of Iguratimod is 25 mg by mouth twice daily, taken in the morning and evening after meals. Some doctors start with 25 mg once daily for 1 to 2 weeks so the patient can tolerate it better, and then increase to 25 mg twice daily. In mild kidney or liver impairment, the dose usually doesn't need to change, but the medicine should still be used with caution. It is not typically recommended for children, because its safety and efficacy haven't been established in them. Liver function, kidney function and blood counts need to be checked regularly during treatment. Iguratimod is often used alone, or together with methotrexate or other DMARDs.