Ibuprofen + Paracetamol
Indications
Ibuprofen + Paracetamol tablet is used for the short-term relief of mild to moderate pain, when ibuprofen or paracetamol taken on its own hasn't worked well enough. This includes migraine, headache, backache, menstrual pain, dental pain, rheumatic and joint pain, muscular pain, cold and flu symptoms, sore throat and fever.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Paracetamol is a para-aminophenol derivative. It relieves pain and reduces fever, and its anti-inflammatory activity is weak. Its pain-relieving effect may come from blocking prostaglandin synthesis in the central nervous system and from modulating the inhibitory descending serotonergic pathways. The fever-reducing effect may be due to less prostaglandin being produced in the hypothalamus.
Ibuprofen is an NSAID with pain-relieving, anti-inflammatory and fever-reducing properties. It inhibits the COX-1 and COX-2 enzymes, and in doing so it also blocks prostaglandin synthesis.
Pregnancy & Breastfeeding
Pregnancy: No well controlled studies have been done in pregnant women exposed to the combination of ibuprofen and paracetamol, so the risk of major birth defects, miscarriage or harmful outcomes for the mother or baby is not known. Avoid this combination in the first six months of pregnancy. In the last three months of pregnancy it is contraindicated.
Lactation: Paracetamol passes into breast milk, but not in an amount that matters clinically. For short-term treatment at the recommended dose, there is no need to stop breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.