Informational only — Not medical advice. Always consult a licensed healthcare provider.

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Human Coagulation Factor VIII

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Indications

Human Coagulation Factor VIII belongs to a group of medicines called clotting factors. It contains human blood coagulation factor VIII, a special protein that helps the blood to clot. The medicine is used to treat and prevent bleeding in patients with haemophilia A. In this condition, bleeding can go on for longer than expected, because the blood has an hereditary lack of coagulation factor VIII.

⚠️ Always consult a registered physician before taking any medicine.

Pregnancy & Breastfeeding

If you are pregnant or breast-feeding, if you think you may be pregnant, or if you are planning to have a baby, talk to your doctor or pharmacist before you take Human Coagulation Factor VIII.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Dosage for the prevention of bleeding If you have severe haemophilia A, you should inject 20 to 40 IU of factor VIII per kg body weight every two or three days for long-term prevention. Your dose should be adjusted according to how you respond. In some cases, shorter gaps between doses or higher doses may be needed. Dosage calculation Always use Human Coagulation Factor VIII exactly as your doctor has told you. If you are not sure, check with your doctor or pharmacist. Factor VIII activity means the amount of factor VIII present in the plasma. It is expressed either as a percentage (compared with normal human blood plasma) or in International Units (IU). The dose of factor VIII is expressed in IU. One IU of factor VIII activity equals the amount of factor VIII in one ml of normal human blood plasma. One IU of factor VIII per kg body weight raises the plasma factor VIII activity by 1.5%-2% of normal activity. To work out your dose, the level of factor VIII activity in your blood plasma is measured. This shows how much the activity needs to be raised. If you are uncertain how much your factor VIII activity has to be raised, or how to calculate your dose, please consult your doctor.