More from Octanate
Other strengths and forms by City Overseas Ltd.
Indications & Uses
Human Coagulation Factor VIII belongs to a group of medicines called clotting factors. It contains human blood coagulation factor VIII, a special protein that helps the blood to clot. The medicine is used to treat and prevent bleeding in patients with haemophilia A. In this condition, bleeding can go on for longer than expected, because the blood has an hereditary lack of coagulation factor VIII.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dosage for the prevention of bleeding
If you have severe haemophilia A, you should inject 20 to 40 IU of factor VIII per kg body weight every two or three days for long-term prevention. Your dose should be adjusted according to how you respond. In some cases, shorter gaps between doses or higher doses may be needed.
Dosage calculation
Always use Human Coagulation Factor VIII exactly as your doctor has told you. If you are not sure, check with your doctor or pharmacist. Factor VIII activity means the amount of factor VIII present in the plasma. It is expressed either as a percentage (compared with normal human blood plasma) or in International Units (IU). The dose of factor VIII is expressed in IU. One IU of factor VIII activity equals the amount of factor VIII in one ml of normal human blood plasma. One IU of factor VIII per kg body weight raises the plasma factor VIII activity by 1.5%-2% of normal activity.
To work out your dose, the level of factor VIII activity in your blood plasma is measured. This shows how much the activity needs to be raised. If you are uncertain how much your factor VIII activity has to be raised, or how to calculate your dose, please consult your doctor.
Side Effects
Like all medicines, Human Coagulation Factor VIII can cause side effects, although not everybody gets them. Hypersensitivity or allergic reactions are rare (they may affect up to 1 in 1,000 people), but they have been seen in patients treated with products that contain factor VIII. Contact your doctor if you get any of these symptoms: being sick (vomiting), burning and stinging at the infusion site, chest tightness, chills, faster heart beat (tachycardia), feeling sick (nausea), feeling of pins and needles (tingling), flushing, headache, hives (urticaria), low blood pressure (hypotension), rash, restlessness, swelling of the face, lips, mouth, tongue or throat which may cause difficulty in swallowing or breathing (angioedema), tiredness (lethargy), wheezing. In very rare cases (may affect up to 1 in 10,000 people), this hypersensitivity may lead to a severe, life-threatening allergic reaction called anaphylaxis. This may include shock, as well as some or all of the symptoms described above. If that happens, contact your doctor immediately or call for an ambulance.
Cautions & Contraindications
Warnings & Precautions
Biological medicines need to be traceable, so the name and the batch number of the product given to the patient should be clearly recorded. Every time Moroctocog alfa (AF-CC) (r-DNA origin) is given, it is strongly recommended that the name on the carton and the batch number are written down. This keeps a link between the patient and the batch of the medicine. Patients can stick one of the peel-off labels from the vial or prefilled syringe into their diary to record the batch number, or use it when reporting any side effects.
Pregnancy & Breastfeeding
If you are pregnant or breast-feeding, if you think you may be pregnant, or if you are planning to have a baby, talk to your doctor or pharmacist before you take Human Coagulation Factor VIII.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Human Coagulation Factor VIII out of the sight and reach of children. Don't use it after the expiry date stated on the label. The expiry date means the last day of that month.
Store it at 2°C to 8°C and do not freeze it. Keep the vials in the outer carton to protect them from light. Use the reconstituted solution immediately, and for a single use only. If the solution looks cloudy or hasn't dissolved completely, don't use it.
Don't throw away any medicines through wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures help to protect the environment.
Common questions about Octanate 500 IU/10 ml
What is Octanate 500 IU/10 ml IV Infusion?
Octanate 500 IU/10 ml IV Infusion is a medicine that contains Human Coagulation Factor VIII. It is made by City Overseas Ltd. It belongs to the Anti-fibrinolytic drugs group of medicines.
What is Octanate used for?
Human Coagulation Factor VIII belongs to a group of medicines called clotting factors. It contains human blood coagulation factor VIII, a special protein that helps the blood to clot.
What are the side effects of Octanate?
Like all medicines, Human Coagulation Factor VIII can cause side effects, although not everybody gets them. Hypersensitivity or allergic reactions are rare (they may affect up to 1 in 1,000 people), but they have been seen in patients treated with products that contain factor VIII.
Can I take Octanate during pregnancy or while breastfeeding?
If you are pregnant or breast-feeding, if you think you may be pregnant, or if you are planning to have a baby, talk to your doctor or pharmacist before you take Human Coagulation Factor VIII. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Octanate?
Keep Human Coagulation Factor VIII out of the sight and reach of children. Don't use it after the expiry date stated on the label.
Do I need a prescription for Octanate?
Octanate is a prescription (Rx) medicine. Take it as your doctor advises.