Indications
Gramicidin, Neomycin and Polymyxin B Sulfates ophthalmic solution is used on the eye to treat superficial infections of the external eye and its adnexa, when the infection is caused by susceptible bacteria. These infections include conjunctivitis, keratitis and keratoconjunctivitis, blepharitis and blepharoconjunctivitis.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Neomycin kills many gram-positive and gram-negative bacteria. It is an aminoglycoside antibiotic, and it stops bacteria making protein by binding to ribosomal RNA, which makes the bacterial genetic code get misread.
Polymyxin B kills a variety of gram-negative organisms. It makes the bacterial cell membrane more permeable by interacting with the phospholipid components of the membrane.
Gramicidin kills a variety of gram-positive organisms. It also makes the cell membrane more permeable, in this case to inorganic cations, by forming a network of channels through the normal lipid bilayer of the membrane.
Pregnancy & Breastfeeding
Pregnancy Category C. No adequate animal reproductive studies have been done with gramicidin, neomycin and polymyxin B. It's also not known whether this product can harm the fetus when given to a pregnant woman, or whether it can affect the ability to reproduce. So it should be given to a pregnant woman only if clearly needed.
Nursing Mothers: It's not known whether this drug passes into human milk. Many drugs do pass into human milk, so caution should be exercised when this product is given to a nursing woman.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.