Fusidic acid + Hydrocortisone
Indications
Fusidic acid + Hydrocortisone is used for skin diseases where a bacterial infection is already there or is likely to develop. These include primary irritant dermatitis, contact allergic dermatitis, eczema (atopic, infantile, discoid and stasis) and seborrhoeic dermatitis.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
This cream combines Fusidic Acid BP 2% and Hydrocortisone Acetate BP 1%. It brings together the strong topical antibacterial action of Fusidic Acid and the anti-inflammatory and anti-pruritic effects of Hydrocortisone Acetate. Applied to the skin, Fusidic Acid works against Staphylococci, Streptococci, Corynebacteria, Neisseria and certain Clostridia and Bacteroides.
Fusidic Acid is an antimicrobial that blocks protein synthesis in the microorganism. It interferes with the translocation step by stabilizing the ribosome-guanosine diphosphate elongation factor G-complex. As a result, aminoacyl t-RNA can't bind to the ribosome, and no more amino acids are passed on to the growing polypeptide.
In humans, Hydrocortisone is the main naturally occurring glucocorticosteroid. At pharmaceutical doses, its chief action is to lower the skin's response to injury, which is its anti-inflammatory effect. It also has immunosuppressant and anti-mitotic actions.
Pregnancy & Breastfeeding
No one has established that Fusidic Acid or topical Hydrocortisone Acetate is safe during pregnancy or breastfeeding. So if this cream is being considered at either time, the doctor needs to weigh the possible benefits against the risks to the unborn baby or the nursing infant.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.