Pricing
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All price changes →Indications & Uses
Fusidic acid + Hydrocortisone is used for skin diseases where a bacterial infection is already there or is likely to develop. These include primary irritant dermatitis, contact allergic dermatitis, eczema (atopic, infantile, discoid and stasis) and seborrhoeic dermatitis.
Pharmacology
This cream combines Fusidic Acid BP 2% and Hydrocortisone Acetate BP 1%. It brings together the strong topical antibacterial action of Fusidic Acid and the anti-inflammatory and anti-pruritic effects of Hydrocortisone Acetate. Applied to the skin, Fusidic Acid works against Staphylococci, Streptococci, Corynebacteria, Neisseria and certain Clostridia and Bacteroides.
Fusidic Acid is an antimicrobial that blocks protein synthesis in the microorganism. It interferes with the translocation step by stabilizing the ribosome-guanosine diphosphate elongation factor G-complex. As a result, aminoacyl t-RNA can't bind to the ribosome, and no more amino acids are passed on to the growing polypeptide.
In humans, Hydrocortisone is the main naturally occurring glucocorticosteroid. At pharmaceutical doses, its chief action is to lower the skin's response to injury, which is its anti-inflammatory effect. It also has immunosuppressant and anti-mitotic actions.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults: Apply the cream to the affected areas 3 times daily and massage it in gently. Use it for 2 weeks. If symptoms improve, a shorter course should be considered.
Children: The cream is not recommended for children under 3 years of age.
Side Effects
Fusidic acid with hydrocortisone can cause mild irritation where it is applied, though this did not usually mean the treatment had to be stopped. Hypersensitivity reactions have been reported only rarely. The side effects are mostly local. They include dryness, itching, burning, local irritation, striae, skin atrophy, atrophy of subcutaneous tissues, telangiectasia, hypertrichosis, change in pigmentation and secondary infection. If the preparation is applied to the face, acne rosacea or perioral dermatitis can occur.
Cautions & Contraindications
Warnings & Precautions
Don't use Fusidic Acid and Hydrocortisone Acetate in or near the eye, because the fusidic acid can irritate the conjunctiva. Enough of the medicine may also be absorbed into the body to cause adrenal suppression and other systemic effects. This can happen when it is used under an occlusive dressing, over large areas, or on the face, scalp, axillae and scrotum.
Contraindications
Don't use this cream if you are allergic to Fusidic Acid, Hydrocortisone Acetate or any other ingredient in it. Like other creams that combine an antibiotic with a corticosteroid, it must also not be used on bacterial infections caused by organisms that the antibiotic doesn't work against. The same applies to fungal infections, tuberculosis of the skin, syphilitic skin infections, chicken pox, eruptions that follow vaccinations, and viral diseases of the skin in general.
Pregnancy & Breastfeeding
No one has established that Fusidic Acid or topical Hydrocortisone Acetate is safe during pregnancy or breastfeeding. So if this cream is being considered at either time, the doctor needs to weigh the possible benefits against the risks to the unborn baby or the nursing infant.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Use in children: In clinical trials of Fusidic Acid and Hydrocortisone Acetate, children aged 3 years and over did not show any higher rate of adverse effects. For children under 3 years, there are no data from randomized, controlled clinical trials on the safety and efficacy of Fusidic acid + Hydrocortisone.
Storage
Keep Fusidic acid + Hydrocortisone below 30°C, and away from light and moisture. Always keep it out of the reach of children.
Common questions about Fusidate H 2%+1%
What is Fusidate H 2%+1% Cream?
Fusidate H 2%+1% Cream is a medicine that contains Fusidic acid + Hydrocortisone. It is made by Aristopharma Limited. It belongs to the Hydrocortisone & Combined preparations group of medicines.
What is Fusidate H used for?
Fusidic acid + Hydrocortisone is used for skin diseases where a bacterial infection is already there or is likely to develop. These include primary irritant dermatitis, contact allergic dermatitis, eczema (atopic, infantile, discoid and stasis) and seborrhoeic dermatitis.
What are the side effects of Fusidate H?
Fusidic acid with hydrocortisone can cause mild irritation where it is applied, though this did not usually mean the treatment had to be stopped. Hypersensitivity reactions have been reported only rarely.
Can I take Fusidate H during pregnancy or while breastfeeding?
No one has established that Fusidic Acid or topical Hydrocortisone Acetate is safe during pregnancy or breastfeeding. So if this cream is being considered at either time, the doctor needs to weigh the possible benefits against the risks to the unborn baby or the nursing infant. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Fusidate H?
Keep Fusidic acid + Hydrocortisone below 30°C, and away from light and moisture. Always keep it out of the reach of children.
Do I need a prescription for Fusidate H?
Fusidate H is a prescription (Rx) medicine. Take it as your doctor advises.