Fluphenazine + Nortriptyline
Indications
Fluphenazine + Nortriptyline is used for mild to moderate mixed anxiety and depression. Doctors also prescribe it for emotional disturbance, sleep disorder and gastric problems.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Nortriptyline hydrochloride is a tricyclic antidepressant. It blocks the uptake of norepinephrine and serotonin at nerve terminals. Its parent compound, amitriptyline, is equally potent in inhibiting the uptake of both. Nortriptyline is different, because it has a greater effect on norepinephrine reuptake than on serotonin reuptake.
Fluphenazine is a tranquilizer of the phenothiazine type, with a piperazine side chain. It acts mainly as a neuroleptic drug, and its main therapeutic effect is believed to come from potent dopamine (specially D2) receptor antagonism.
Pregnancy & Breastfeeding
Nobody has yet established whether fluphenazine + nortriptyline is safe in human pregnancy. The combination is also not recommended during breastfeeding, because the medicine passes into breast milk.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.