Pricing
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Same active ingredient — pay up to 11% less
These brands contain the same active ingredient (Fluphenazine + Nortriptyline). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Fluphenazine + Nortriptyline is used for mild to moderate mixed anxiety and depression. Doctors also prescribe it for emotional disturbance, sleep disorder and gastric problems.
Pharmacology
Nortriptyline hydrochloride is a tricyclic antidepressant. It blocks the uptake of norepinephrine and serotonin at nerve terminals. Its parent compound, amitriptyline, is equally potent in inhibiting the uptake of both. Nortriptyline is different, because it has a greater effect on norepinephrine reuptake than on serotonin reuptake.
Fluphenazine is a tranquilizer of the phenothiazine type, with a piperazine side chain. It acts mainly as a neuroleptic drug, and its main therapeutic effect is believed to come from potent dopamine (specially D2) receptor antagonism.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults take one tablet 2 to 3 times a day.
Side Effects
Tardive dyskinesia has been reported with phenothiazine therapy, usually after long courses given at doses high enough to control a psychotic illness. Blood dyscrasia, Malignant Neuroleptic syndrome and sudden death have also been reported, but only rarely. Agranulocytosis is a rare but potentially fatal adverse effect of Nortriptyline Hydrochloride.
Cautions & Contraindications
Warnings & Precautions
Take care when giving Fluphenazine + Nortriptyline to patients with glaucoma, prostate enlargement, cardiac failure or a previous myocardial infarction. The same care applies if the patient is also taking CNS depressants. The medicine can dull alertness, so it may affect a person's ability to drive a car or operate machinery.
Contraindications
Fluphenazine + Nortriptyline should not be used in people with a history of gradual epilepsy or organic brain damage, blood dyscrasia, severe cardiac insufficiency, or renal or liver damage. It is also contraindicated in patients taking a monoamine oxidase inhibitor (MAOI), in younger children, and in anyone with hypersensitivity to any component of the preparation.
Pregnancy & Breastfeeding
Nobody has yet established whether fluphenazine + nortriptyline is safe in human pregnancy. The combination is also not recommended during breastfeeding, because the medicine passes into breast milk.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Fluphenazine + Nortriptyline below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Common questions about Fresh 0.5 mg+10 mg
What is Fresh 0.5 mg+10 mg Tablet?
Fresh 0.5 mg+10 mg Tablet is a medicine that contains Fluphenazine + Nortriptyline. It is made by Nipa Pharmaceuticals Ltd. It belongs to the Combined anxiolytics & anti-depressant drugs group of medicines.
What is Fresh used for?
Fluphenazine + Nortriptyline is used for mild to moderate mixed anxiety and depression. Doctors also prescribe it for emotional disturbance, sleep disorder and gastric problems.
What are the side effects of Fresh?
Tardive dyskinesia has been reported with phenothiazine therapy, usually after long courses given at doses high enough to control a psychotic illness. Blood dyscrasia, Malignant Neuroleptic syndrome and sudden death have also been reported, but only rarely.
Can I take Fresh during pregnancy or while breastfeeding?
Nobody has yet established whether fluphenazine + nortriptyline is safe in human pregnancy. The combination is also not recommended during breastfeeding, because the medicine passes into breast milk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Fresh?
Store Fluphenazine + Nortriptyline below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Is there a cheaper medicine with the same ingredient?
Flutrip by General Pharmaceuticals Ltd. has the same ingredient and strength for ৳0.71 per unit, compared with ৳0.80 for Fresh. Ask your doctor or pharmacist before switching.
Do I need a prescription for Fresh?
Fresh is a prescription (Rx) medicine. Take it as your doctor advises.