Indications
Enteca (entecavir monohydrate) is used to treat long-term (chronic) hepatitis B virus infection in adults and in children aged 2 years and older. It is meant for people whose virus is actively multiplying in the body, and who also have either a lasting rise in the liver enzymes ALT or AST in the blood, or liver disease that is active on histology (the examination of liver tissue).
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Entecavir competes with the natural substrate deoxyguanosine triphosphate, and in this way it functionally inhibits all three activities of the HBV polymerase (reverse transcriptase, rt). These are base priming, reverse transcription of the negative strand from the pregenomic messenger RNA, and synthesis of the positive strand of HBV DNA. Once kinases activate the drug, it can be built into the DNA, and the final effect is that HBV polymerase activity is inhibited.
Pregnancy & Breastfeeding
There are no data on how Entecavir affects the transmission of HBV from mother to infant, so appropriate care should be taken. It isn't known whether Entecavir is excreted in human milk. Mothers should be told not to breastfeed while they are taking it.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.