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Same active ingredient — pay up to 1% less
These brands contain the same active ingredient (Entecavir Monohydrate). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Enviral
Other strengths and forms by Opsonin Pharma Limited
Indications & Uses
Enteca (entecavir monohydrate) is used to treat long-term (chronic) hepatitis B virus infection in adults and in children aged 2 years and older. It is meant for people whose virus is actively multiplying in the body, and who also have either a lasting rise in the liver enzymes ALT or AST in the blood, or liver disease that is active on histology (the examination of liver tissue).
Pharmacology
Entecavir competes with the natural substrate deoxyguanosine triphosphate, and in this way it functionally inhibits all three activities of the HBV polymerase (reverse transcriptase, rt). These are base priming, reverse transcription of the negative strand from the pregenomic messenger RNA, and synthesis of the positive strand of HBV DNA. Once kinases activate the drug, it can be built into the DNA, and the final effect is that HBV polymerase activity is inhibited.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The recommended dose of Entecavir for chronic hepatitis B virus infection is 0.5 mg once daily in adults and adolescents 16 years of age who have not had nucleoside treatment before. If the infection is Lamivudine-refractory, or there are known Lamivudine or Telbivudine resistance mutations, the dose is 1 mg once daily. Adults with decompensated liver disease also take 1 mg once daily.
Entecavir should be taken on an empty stomach, which means at least 2 hours after a meal or 2 hours before the next meal.
Missed dose: if it is almost time for the next dose, skip the missed one and take the next dose at the proper time. Nobody should take a double dose to make up for a missed dose.
Side Effects
People taking Entecavir Monohydrate most often report headache, fatigue, dizziness and nausea.
Cautions & Contraindications
Warnings & Precautions
Lactic acidosis Lactic acidosis and severe hepatomegaly with steatosis have been reported with nucleoside analogues, whether used alone or together with antiretrovirals. Some of these cases were fatal. Exacerbations of hepatitis after discontinuation of treatment Severe acute exacerbations of hepatitis B have been reported in patients who stopped anti-hepatitis B therapy. This includes patients who stopped Enteca (Entecavir Monohydrate).
Contraindications
Don't give Entecavir to anyone who has already shown an allergic reaction (hypersensitivity) to Entecavir or to any other component of the product.
Pregnancy & Breastfeeding
There are no data on how Entecavir affects the transmission of HBV from mother to infant, so appropriate care should be taken. It isn't known whether Entecavir is excreted in human milk. Mothers should be told not to breastfeed while they are taking it.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
No overdose of Entecavir Monohydrate has been reported in patients. In healthy subjects, doses of up to 20 mg daily for up to 14 days, and single doses of up to 40 mg, caused no unexpected adverse events. If an overdose does happen, the patient must be watched for signs of toxicity and given standard supportive treatment as necessary.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Entecavir Monohydrate in a dry place, below 30°C. Keep it away from light, and keep it out of the reach of children.
Drug Interactions
Common questions about Enviral 1 mg
What is Enviral 1 mg Tablet?
Enviral 1 mg Tablet is a medicine that contains Entecavir Monohydrate. It is made by Opsonin Pharma Limited. It belongs to the Hepatic viral infections (Hepatitis B) group of medicines.
What is Enviral used for?
Enteca (entecavir monohydrate) is used to treat long-term (chronic) hepatitis B virus infection in adults and in children aged 2 years and older. It is meant for people whose virus is actively multiplying in the body, and who also have either a lasting rise in the liver enzymes ALT or AST in the blood, or liver disease that is active on histology (the examination of liver tissue).
What are the side effects of Enviral?
People taking Entecavir Monohydrate most often report headache, fatigue, dizziness and nausea.
Can I take Enviral during pregnancy or while breastfeeding?
There are no data on how Entecavir affects the transmission of HBV from mother to infant, so appropriate care should be taken. It isn't known whether Entecavir is excreted in human milk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Enviral?
No overdose of Entecavir Monohydrate has been reported in patients. In healthy subjects, doses of up to 20 mg daily for up to 14 days, and single doses of up to 40 mg, caused no unexpected adverse events. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Enviral?
Store Entecavir Monohydrate in a dry place, below 30°C. Keep it away from light, and keep it out of the reach of children.
Can I take other medicines with Enviral?
Some medicines can interact with Entecavir Monohydrate, for example: Adefovir Dipivoxil, Lamivudine. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Barcavir by Incepta Pharmaceuticals Ltd. has the same ingredient and strength for ৳90.00 per unit, compared with ৳90.95 for Enviral. Ask your doctor or pharmacist before switching.
Do I need a prescription for Enviral?
Enviral is a prescription (Rx) medicine. Take it as your doctor advises.