Community data
Updated 23 hours ago
Indications
Eluxadoline is used in adults to treat irritable bowel syndrome with diarrhea (IBS-D).
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Eluxadoline acts as an agonist at the mu-opioid receptor and the kappa opioid receptor, and as an antagonist at the delta opioid receptor. It works directly in the intestine, where it slows peristalsis. It also makes the nerves in the intestine less sensitive to stimulation.
Pregnancy & Breastfeeding
Pregnancy: Not established.
Lactation: Not established.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Adults: The usual dose of eluxadoline is one 75 mg tablet taken by mouth twice a day with food. If a patient develops severe constipation that lasts for more than 4 days, they have to stop the medicine. If a dose is missed, the patient should take the next dose at the regular time and not take two doses together.
Pediatric Use: Safety and effectiveness in pediatric patients have not been established.
Hepatic Impairment: Eluxadoline is contraindicated in patients with severe hepatic impairment.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.