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Other brands with the same active ingredient

These brands contain the same active ingredient (Eluxadoline). Same strength and form. Confirm the switch with your doctor or pharmacist.

Available as: 100 mg

Indications & Uses

luxadin 100 tablet is indicated for:

Pharmacology

Eluxadoline acts as an agonist at the mu-opioid receptor and the kappa opioid receptor, and as an antagonist at the delta opioid receptor. It works directly in the intestine, where it slows peristalsis. It also makes the nerves in the intestine less sensitive to stimulation.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

The usual dose of eluxadoline is one 75 mg tablet taken by mouth twice a day with food. If a patient develops severe constipation that lasts for more than 4 days, they have to stop the medicine. If a dose is missed, the patient should take the next dose at the regular time and not take two doses together.

Pediatric Use: Safety and effectiveness in pediatric patients have not been established.

Hepatic Impairment: Eluxadoline is contraindicated in patients with severe hepatic impairment.

Side Effects

With eluxadoline, the side effects people report most often are constipation, nausea and abdominal pain.

Cautions & Contraindications

Warnings & Precautions

Eluxadoline can cause spasm of the sphincter of Oddi and pancreatitis. Some patients need close monitoring: those without a gallbladder, those with new or worsening abdominal pain with nausea and vomiting, those with acute biliary pain, and those whose liver or pancreatic enzymes have gone up.

Contraindications

Eluxadoline should not be used by people who have, or are suspected to have, a blocked biliary duct, sphincter of Oddi disease or dysfunction, or pancreatitis.

Pregnancy & Breastfeeding

Pregnancy: Not established.

Lactation: Not established.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Storage

Keep Eluxadoline in a cool, dry place and protect it from light. Keep it out of the reach of children.

Drug Interactions

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Moderate Cyclosporine
Moderate Rosuvastatin

Common questions about luxadin 100 tablet 100 mg

What is luxadin 100 tablet 100 mg Tablet?

luxadin 100 tablet 100 mg Tablet is a medicine that contains Eluxadoline. It is made by Square Pharmaceuticals PLC, Gazipur. It belongs to the Carboxylic acids and derivatives group of medicines.

What is luxadin 100 tablet used for?

luxadin 100 tablet is used for: Diarrhea, Irritable Bowel Syndrome.

What are the side effects of luxadin 100 tablet?

With eluxadoline, the side effects people report most often are constipation, nausea and abdominal pain.

Can I take luxadin 100 tablet during pregnancy or while breastfeeding?

Pregnancy: Not established. Lactation: Not established. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

How should I store luxadin 100 tablet?

Keep Eluxadoline in a cool, dry place and protect it from light. Keep it out of the reach of children.

Can I take other medicines with luxadin 100 tablet?

Some medicines can interact with Eluxadoline, for example: Cyclosporine, Rosuvastatin. Tell your doctor or pharmacist about every medicine you take.

Do I need a prescription for luxadin 100 tablet?

luxadin 100 tablet is a prescription (Rx) medicine. Take it as your doctor advises.

Last updated: 15 Aug 2026