Informational only — Not medical advice. Always consult a licensed healthcare provider.

Shasthya স্বাস্থ্য · Health, made simple
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Community data Updated 2 months ago
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Indications

Adiva (efavirenz) is used together with other antiretroviral agents to treat HIV-1 infection. This use rests on plasma HIV-RNA levels and CD4 cell counts measured in controlled studies lasting up to 24 weeks. So far there are no results from controlled trials that look at long-term suppression of HIVRNA with Adiva.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) active against HIV-1. It blocks RNA and DNA dependent polymerase activities, including HIV-1 replication.

Pregnancy & Breastfeeding

Efavirenz is classed as Category D in pregnancy. This means there is positive evidence of risk to the human fetus, yet the benefits may still outweigh the risk for some pregnant women. That judgement is usually made when the drug is needed in a life-threatening situation, or for a serious disease where safer medicines cannot be used or do not work.

Lactation

Efavirenz may pass into breast milk and cause serious harm to the baby. It should not be used during lactation.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Dosage in Adults: The recommended dose of Efavirenz is 600 mg taken by mouth once daily, combined with a protease inhibitor and/or nucleoside analogue reverse transcriptase inhibitors (NRTIs). Dosage in Pediatric Patients: For children 3 years of age or older weighing between 10 and 40 kg, the recommended dose of Efavirenz depends on body weight. Children weighing 10 to less than 15 kg should receive 200 mg once daily. Those weighing 15 to less than 20 kg should receive 250 mg once daily. Those weighing 20 to less than 25 kg should receive 300 mg once daily. Those weighing 25 to less than 32.5 kg should receive 350 mg once daily. Those weighing 32.5 to less than 40 kg should receive 400 mg once daily. Children weighing 40 kg or more, as well as those weighing more than 40 kg, should receive the same dose used in adults, which is 600 mg once daily.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.