Dotinurad

Adults: The usual adult dose of Dotinurad is 0.5 mg, taken by mouth once a day. After that, the doctor raises the dose step by step as needed, checking the blood uric acid level along the way. The maintenance dose is usually 2 mg once a day. It may be adjusted according to the patient's condition, but the maximum is 4 mg once a day. Precautions related to dosage and administration In the early stages of treatment with urate-lowering drugs, a rapid fall in blood uric acid can bring on gouty arthritis (a gout attack). For this reason the dose is increased gradually, to 1 mg once a day after 2 weeks and to 2 mg once a day after 6 weeks. Patients should be watched carefully after each increase in dose. Missing dose If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one and carry on with your regular schedule. Never take two doses at once. Don't stop taking this medicine unless your doctor advises it. Overdose If you accidentally take too much, consult your doctor or pharmacist.