Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications

Proston is used to help start labour, and it widens the cervix so delivery is easier. It is also used to bring on an abortion at about 12 to 20 weeks of pregnancy. Another use is to help clear the vagina after a miscarriage.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Dinoprostone is a substance that the body makes naturally. It acts as a local hormone, meaning it works on the tissue where it is found rather than travelling around the whole body. It relaxes the muscles of the cervix and makes them open up. Over time, this helps the muscle of the uterus begin to contract during labour. Its action is much like that of PGE2, also known as prostaglandin E2.

Pregnancy & Breastfeeding

Dinoprostone falls under FDA pregnancy category C. It isn't recommended for use during pregnancy, labor, or delivery, and it should also be avoided by mothers who are breastfeeding.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: For adult patients, the recommended dose of Dinoprostone gel is 0.5 mg. After the gel is placed, the patient should remain lying on her back for 10 to 15 minutes to minimize gel leakage. In geriatrics (patients over 65 years of age), Dinoprostone gel has not been studied and is not recommended for use. In pediatrics (patients under 18 years of age), Dinoprostone gel has not been studied and is not recommended for use.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.

Key Interactions

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