Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Difamilast is an ointment that you apply to the skin to treat atopic dermatitis, which most people know as eczema.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Difamilast is a phosphodiesterase 4 (PDE4) inhibitor. It raises the concentration of cyclic adenosine 3',5'-monophosphate (cAMP), and this in turn suppresses the production of inflammatory cytokines. That is how difamilast works in the treatment of atopic dermatitis.

Pregnancy & Breastfeeding

Difamilast isn't recommended for women who are pregnant or who may possibly be pregnant. For women who are breastfeeding, the safety of difamilast has not been fully established.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: For adults, Difamilast 1% ointment is applied to the affected area twice daily, using an appropriate amount each time. For children, the dose is an appropriate amount of Difamilast 0.3% ointment on the affected area, also twice daily.