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Other strengths and forms by Eskayef Pharmaceuticals Ltd.
Indications & Uses
Atofix is indicated for:
Pharmacology
Difamilast is a phosphodiesterase 4 (PDE4) inhibitor. It raises the concentration of cyclic adenosine 3',5'-monophosphate (cAMP), and this in turn suppresses the production of inflammatory cytokines. That is how difamilast works in the treatment of atopic dermatitis.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
For adults, Difamilast 1% ointment is applied to the affected area twice daily, using an appropriate amount each time. For children, the dose is an appropriate amount of Difamilast 0.3% ointment on the affected area, also twice daily.
Side Effects
Difamilast is well tolerated when used at the recommended dose. At a higher dose it may cause mild skin reactions where it is applied, such as redness, burning or stinging.
Cautions & Contraindications
Warnings & Precautions
Difamilast ointment is for external use only. Don't use it by mouth, in the eyes or in the vagina. If the person shows any sign of hypersensitivity to Difamilast, stop the treatment.
Contraindications
Don't give Difamilast to anyone who is known to be allergic to the medicine.
Pregnancy & Breastfeeding
Difamilast isn't recommended for women who are pregnant or who may possibly be pregnant. For women who are breastfeeding, the safety of difamilast has not been fully established.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Difamilast below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Common questions about Atofix 1%
What is Atofix 1% Ointment?
Atofix 1% Ointment is a medicine that contains Difamilast. It is made by Eskayef Pharmaceuticals Ltd.
What is Atofix used for?
Atofix is used for: Eczema.
What are the side effects of Atofix?
Difamilast is well tolerated when used at the recommended dose. At a higher dose it may cause mild skin reactions where it is applied, such as redness, burning or stinging.
Can I take Atofix during pregnancy or while breastfeeding?
Difamilast isn't recommended for women who are pregnant or who may possibly be pregnant. For women who are breastfeeding, the safety of difamilast has not been fully established. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Atofix?
Store Difamilast below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Do I need a prescription for Atofix?
Atofix is a prescription (Rx) medicine. Take it as your doctor advises.