Informational only — Not medical advice. Always consult a licensed healthcare provider.

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Community data Updated 23 hours ago
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Indications

Type 2 Diabetes Mellitus Diabetes Mellitus

Dapagliflozin Propanediol is used together with diet and exercise to help control blood sugar in adults with type 2 diabetes mellitus.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Dapagliflozin is an inhibitor of Sodium-glucose co-transporter 2 (SGLT2). This transporter sits in the proximal renal tubules of the kidney, and it handles most of the reabsorption of filtered glucose from the tubular lumen. Dapagliflozin blocks SGLT2, so less of the filtered glucose is taken back up and the renal threshold for glucose (RTG) falls. The result is that more glucose leaves the body in the urine.

Pregnancy & Breastfeeding

Dapagliflozin is a pregnancy category C medicine. There aren't enough data or well controlled studies on its use in pregnant women. So it should be used during pregnancy only if the possible benefit justifies the possible risk to the fetus. It isn't known whether Dapagliflozin passes into human milk, but it should not be used while a woman is breastfeeding.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Adults: The recommended starting dose of Dapagliflozin is 5 mg once daily, taken in the morning, with or without food. If a patient tolerates 5 mg once daily and needs better glycemic control, the dose can be increased to 10 mg once daily. Patients with Renal Impairment: Renal function should be assessed before Dapagliflozin treatment is started, and then checked from time to time. Dapagliflozin should not be started in patients with an eGFR less than 60 mL/min/1.73 m2. No dose adjustment is needed in patients with mild renal impairment (eGFR of 60 mL/min/1.73 m2 or greater). Dapagliflozin should be stopped when eGFR stays persistently below 60 mL/min/1.73 m2. Children: The safety and efficacy of Dapagliflozin in children and adolescents (<18 years) have not been established.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.