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These brands contain the same active ingredient (Dapagliflozin Propanediol). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Glycema
Other strengths and forms by Advanced Chemical Industries PLC.
Indications & Uses
Glycema is indicated for:
Pharmacology
Dapagliflozin is an inhibitor of Sodium-glucose co-transporter 2 (SGLT2). This transporter sits in the proximal renal tubules of the kidney, and it handles most of the reabsorption of filtered glucose from the tubular lumen. Dapagliflozin blocks SGLT2, so less of the filtered glucose is taken back up and the renal threshold for glucose (RTG) falls. The result is that more glucose leaves the body in the urine.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults: The recommended starting dose of Dapagliflozin is 5 mg once daily, taken in the morning, with or without food. If a patient tolerates 5 mg once daily and needs better glycemic control, the dose can be increased to 10 mg once daily.
Patients with Renal Impairment: Renal function should be assessed before Dapagliflozin treatment is started, and then checked from time to time. Dapagliflozin should not be started in patients with an eGFR less than 60 mL/min/1.73 m2. No dose adjustment is needed in patients with mild renal impairment (eGFR of 60 mL/min/1.73 m2 or greater). Dapagliflozin should be stopped when eGFR stays persistently below 60 mL/min/1.73 m2.
Children: The safety and efficacy of Dapagliflozin in children and adolescents (<18 years) have not been established.
Side Effects
The most common side effects of Dapagliflozin Propanediol are hypotension, ketoacidosis, acute kidney injury and impairment in renal function, urosepsis and pyelonephritis, and hypoglycemia when it is used together with insulin and insulin secretagogues. Genital mycotic infections, increases in low-density lipoprotein cholesterol (LDL-C), nasopharyngitis, urinary tract infection and bladder cancer are also listed.
Cautions & Contraindications
Warnings & Precautions
Hypotension: Before starting Dapagliflozin Propanediol, check the volume status and correct hypovolemia in elderly patients, in patients with renal impairment or low systolic blood pressure, and in patients who are on diuretics. Monitor for signs and symptoms during therapy. Impairment in renal function: Monitor renal function during therapy. Hypoglycemia: If a patient is taking insulin or an insulin secretagogue along with this medicine, consider a lower dose of the insulin or the insulin secretagogue to reduce the risk of hypoglycemia. Bladder Cancer: An imbalance in bladder cancers was observed in clinical trials. Dapagliflozin Propanediol should not be used in patients with active bladder cancer, and it should be used with caution in patients with a prior history of bladder cancer. Macrovascular outcomes: No clinical studies have established conclusive evidence of macrovascular risk reduction with this medicine or with any other antidiabetic drug.
Contraindications
Dapagliflozin Propanediol must not be given to anyone who is known to be hypersensitive to dapagliflozin or to any of the excipients in the product. It is also contraindicated in severe renal impairment and in end-stage renal disease, and in patients who are on dialysis.
Pregnancy & Breastfeeding
Dapagliflozin is a pregnancy category C medicine. There aren't enough data or well controlled studies on its use in pregnant women. So it should be used during pregnancy only if the possible benefit justifies the possible risk to the fetus. It isn't known whether Dapagliflozin passes into human milk, but it should not be used while a woman is breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Dapagliflozin Propanediol in a cool, dry place, below 30°C, and protect it from light. Store it where children can't reach it.
Drug Interactions
Common questions about Glycema 5 mg
What is Glycema 5 mg Tablet?
Glycema 5 mg Tablet is a medicine that contains Dapagliflozin Propanediol. It is made by Advanced Chemical Industries PLC. It belongs to the Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors group of medicines.
What is Glycema used for?
Glycema is used for: Type 2 Diabetes Mellitus, Diabetes Mellitus.
What are the side effects of Glycema?
The most common side effects of Dapagliflozin Propanediol are hypotension, ketoacidosis, acute kidney injury and impairment in renal function, urosepsis and pyelonephritis, and hypoglycemia when it is used together with insulin and insulin secretagogues. Genital mycotic infections, increases in low-density lipoprotein cholesterol (LDL-C), nasopharyngitis, urinary tract infection and bladder cancer are also listed.
Can I take Glycema during pregnancy or while breastfeeding?
Dapagliflozin is a pregnancy category C medicine. There aren't enough data or well controlled studies on its use in pregnant women. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Glycema?
Keep Dapagliflozin Propanediol in a cool, dry place, below 30°C, and protect it from light. Store it where children can't reach it.
Can I take other medicines with Glycema?
Some medicines can interact with Dapagliflozin Propanediol, for example: Pioglitazone, Valsartan, Mefenamic Acid, Insulin (Human) 30/70, Rifampicin. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Dapatab by Ibn Sina Pharmaceutical Ind. Ltd. has the same ingredient and strength for ৳10.00 per unit, compared with ৳20.00 for Glycema. Ask your doctor or pharmacist before switching.
Do I need a prescription for Glycema?
Glycema is a prescription (Rx) medicine. Take it as your doctor advises.