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Community data Updated 23 hours ago

Dalteparin Sodium

Parenteral anti-coagulants Prescription
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Indications

Angina Pectoris Deep Vein Thrombosis

Dalteparin Sodium is used for prophylaxis of clotting in extracorporeal circulation in haemodialysis or haemofiltration, and for prophylaxis of clotting in extracorporeal circulation in haemodialysis or haemofiltration once more. It is also used in unstable angina, for prophylaxis of venous thromboembolism during surgical procedures, and in venous thromboembolism.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Dalteparin Na is an antithrombotic medicine. It works mainly by boosting the way antithrombin inhibits factor Xa and thrombin. Its effect on factor Xa inhibition is relatively stronger than its effect on prolonging aPTT.

Pregnancy & Breastfeeding

Dalteparin Sodium is Pregnancy Category B. This means one of two things. Either animal-reproduction studies have not shown a foetal risk, but there are no controlled studies in pregnant women. Or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester, and there is no evidence of a risk in later trimesters.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Dalteparin Sodium is given by the intravenous route for prophylaxis of clotting in extracorporeal circulation in haemodialysis or haemofiltration. The dose is 30 to 40 U/kg as an IV injection, then 10 to 15 U/kg/hr as an IV infusion. By the subcutaneous route, for venous thromboembolism, the dose is 200 U/kg/day, given as a single dose or in 2 divided doses, in pregnant and high-risk patients. The maximum is 18,000 U/day. For prophylaxis of venous thromboembolism during surgical procedures, the dose depends on the risk. In moderate risk, give 2,500 U 1 to 2 hr pre-op, then 2,500 U once daily for 5 to 7 days or until the patient is fully ambulant. In high risk, give 2,500 U 1 to 2 hr before and 8 to 12 hr after the procedure, then 5,000 U daily. For unstable angina, the dose is 120 U/kg 12 hrly, continued for 5 to 8 days with low-dose aspirin. The maximum here is 10,000 U 12 hrly.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.