Indications
Conjugated Estrogen + Bazedoxifene is used to treat moderate to severe vasomotor symptoms linked to menopause. It is also used to prevent osteoporosis after menopause.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Conjugated Estrogens and Bazedoxifene work by binding to the estrogen receptors (ER) α and β and activating them. Bazedoxifene is an estrogen agonist / antagonist. That means it acts as an agonist in some estrogen-sensitive tissues and as an antagonist in others (the uterus, for example).
Pregnancy & Breastfeeding
Conjugated Estrogen + Bazedoxifene is Pregnancy Category X. Women who are pregnant, or who may become pregnant, must not use it.
Women who are breastfeeding should not use Conjugated Estrogen + Bazedoxifene either. It isn't known whether the drug passes into human milk. Estrogen given to nursing mothers has been shown to reduce both the quantity and the quality of the milk.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.