Clindamycin + Benzoyl peroxide

Pregnancy: There isn't enough data on the use of Benzoyl Peroxide 5% & Clindamycin 1% gel in pregnant women. No animal reproductive or developmental studies have been done with this gel or with benzoyl peroxide. Data on clindamycin and benzoyl peroxide used alone in pregnant women are limited. A small number of pregnancies exposed to clindamycin in the first trimester show no adverse effects of clindamycin on the pregnancy or on the health of the foetus or new-born child. Reproduction studies in rats and mice, using subcutaneous and oral doses of clindamycin, found no evidence of impaired fertility or harm to the foetus from clindamycin. The safety of Benzoyl Peroxide 5% & Clindamycin 1% gel in human pregnancy has not been established. So the gel should be prescribed to pregnant women only after the physician in charge has carefully weighed the risk against the benefit.

Breastfeeding: Benzoyl Peroxide 5% & Clindamycin 1% gel has not been studied during breastfeeding. Clindamycin and benzoyl peroxide are absorbed through the skin only in low amounts, but it is not known whether either one passes into human milk after the gel is used. Clindamycin has been reported to appear in breast milk after oral and parenteral use. For this reason, the gel should be used during lactation only if the expected benefit justifies the potential risk to the infant. The gel should not be applied to the breast area, so that the infant does not swallow it by accident.

Fertility: There are no data on the effect of Benzoyl Peroxide 5% & Clindamycin 1% gel on fertility in humans.