Cefpodoxime Proxetil

Adults: Adults and adolescents (13 years and older) The dose of Cefpodoxime Proxetil depends on the infection being treated. For pharyngitis/tonsillitis, it is 100 mg 12 hourly for 5 to 10 days. Acute maxillary sinusitis needs 200 mg 12 hourly for 10 days, and community-acquired pneumonia needs 200 mg 12 hourly for 14 days. For acute bacterial exacerbations of chronic bronchitis, the dose is 200 mg 12 hourly for 10 days. Skin and skin structure infections need 400 mg 12 hourly for 7 to 14 days. Uncomplicated urinary tract infection is treated with 100 mg 12 hourly for 7 days. Uncomplicated gonorrhea and rectal gonococcal infections in women are each treated with a single dose of 200 mg. Infants and pediatric patients (2 months to 12 years) For acute otitis media, the dose is 5 mg/kg body weight 12 hourly for 5 days. Pharyngitis/tonsillitis is treated with 5 mg/kg body weight 12 hourly for 5 to 10 days, and acute maxillary sinusitis with 5 mg/kg body weight 12 hourly for 10 days. Patients with renal dysfunction In severe renal impairment (creatinine clearance <30 ml/min), the dosing interval should be increased to 24 hourly. Patients with liver cirrhosis The pharmacokinetics of Cefpodoxime Proxetil in cirrhotic patients are similar to those in healthy subjects, so dose adjustment is not necessary in this population.