Indications
Cabolin is used to stop breast milk production (lactation) soon after childbirth, stillbirth, abortion or miscarriage. It can also be used by mothers who choose not to continue breastfeeding. Beyond this, Cabolin is used to treat other conditions caused by hormonal disturbances that lead to abnormally high levels of prolactin.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Cabergoline is a dopamine receptor agonist. The anterior pituitary's secretion of prolactin is mainly under hypothalamic inhibitory control, likely exerted through dopamine release from tuberoinfundibular neurons. Cabergoline is a long acting dopamine receptor agonist with a high affinity for D2 receptors. In vitro studies show that Cabergoline directly inhibits prolactin secretion by rat pituitary lactotrophs. Cabergoline also decreased serum prolactin levels in reserpinized rats. Receptor binding studies indicate that Cabergoline has low affinity for dopamine D1, α1 and α2 adrenergic, and 5HT1, 5HT2 serotonin receptors.
Pregnancy & Breastfeeding
If you are pregnant or planning to become pregnant, talk to your doctor before starting treatment with Cabergoline, even though it falls under pregnancy category B. The patient should be checked to make sure she is not pregnant before Cabergoline is started. She should also avoid becoming pregnant for at least one month after she stops taking Cabergoline. Cabergoline will stop the body from producing milk, so anyone who plans to breastfeed should not take it.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.