Indications
Biphasic Insulin Aspart (rDNA) injection is used to improve glycemic control in adults and children who have type 1 diabetes mellitus. It is also used for adults with type 2 diabetes mellitus.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Biphasic Insulin Aspart (30% Insulin Aspart and 70% Insulin Aspart Protamine, rDNA) is a human insulin analog suspension. It contains 30% soluble Insulin Aspart and 70% Insulin Aspart Protamine crystals. This medicine lowers blood glucose, and it has an earlier onset and an intermediate duration of action.
Insulin Aspart is homologous with regular human insulin, with one exception: the proline in position B28 is replaced by aspartic acid. It is made by recombinant DNA technology using Saccharomyces cerevisiae (baker's yeast).
The primary function of insulin, including Insulin Aspart, is to regulate glucose metabolism. Insulin and its analogs lower blood glucose by stimulating peripheral glucose uptake, mainly by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulin also inhibits lipolysis and proteolysis, and it enhances protein synthesis.
Pregnancy & Breastfeeding
Biphasic Insulin Aspart is pregnancy category B. Blood glucose needs careful monitoring in pregnant women, because insulin requirements change at different stages of pregnancy. So women taking insulin aspart should be told to inform their doctor if they plan to become pregnant, or if they become pregnant while on it.
Lactation: It is not known whether insulin aspart passes into human milk, as human insulin does. There are no adequate and well-controlled studies of insulin aspart in breastfeeding women. Women who are breastfeeding may need their insulin doses adjusted.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.