Azelastine Hydrochloride + Fluticasone Propionate
Indications
Azelastine Hydrochloride + Fluticasone Propionate nasal spray is used to relieve the symptoms of seasonal allergic rhinitis in people aged 6 years and older. It is meant for those who need treatment with both Azelastine Hydrochloride and Fluticasone Propionate to get symptom relief.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Azelastine Hydrochloride blocks histamine H1 receptors, as shown in isolated tissues. Its main metabolite, desmethylazelastine, has the same H1-receptor blocking activity.
Fluticasone Propionate is a synthetic trifluorinated corticosteroid that reduces inflammation. Exactly how it affects the symptoms of allergic rhinitis is not known. Corticosteroids have been shown to act on many cell types involved in inflammation (for example mast cells, eosinophils, neutrophils, macrophages and lymphocytes etc.) and on many mediators (for example histamine, eicosanoids, leukotrienes and cytokines).
Pregnancy & Breastfeeding
Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray is pregnancy category C. No adequate and well-controlled clinical trials have been done in pregnant women, either with the combination or with Azelastine Hydrochloride only or Fluticasone Propionate only. So the spray should be used in pregnancy only if the possible benefit to the mother justifies the possible risk to the fetus.
Nursing Mothers
It isn't known whether Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray passes into human breast milk. Many drugs do pass into human milk, so caution should be exercised when the spray is given to a nursing woman.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.