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Amino acids, Glucose & Electrolytes

Parenteral nutritional preparations Prescription

Indications

Amino acids, glucose and electrolytes is given as a source of all three in adults and children who need nutrition through a drip into the vein (IV nutrition). It suits patients whose amino acid needs are at the basal level.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

A crystalline amino acid solution supplies crystalline amino acids to support protein synthesis and wound healing, and to slow down the rate at which the body breaks down its own protein (endogenous protein catabolism). When amino acids are given through a central venous infusion together with concentrated dextrose, electrolytes, vitamins, trace metals and ancillary fat supplements, this makes up total parenteral nutrition (TPN). Amino acids can also be given through a peripheral vein, with dextrose and maintenance electrolytes.

Pregnancy & Breastfeeding

Amino acid solution has been given safely and successfully to pregnant women, and this has been reported in humans. No animal reproduction studies have been carried out with the 7% amino acid IV infusion with 10% glucose & electrolytes.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: For adults, the dose of Amino acids, Glucose & Electrolytes depends on the nitrogen needed to maintain body protein mass, and that depends on the patient's condition (nutritional state and degree of metabolic stress). The requirement is 0.10 to 0.15 g nitrogen/kg/day when there is no metabolic stress or only minor stress and the nutritional state is normal. It is 0.15 to 0.20 g nitrogen/kg/day with moderate metabolic stress, with or without malnutrition. In severe catabolism, as in burns, sepsis and trauma, it goes up to 0.20 to 0.25 g nitrogen/kg/day. The dosage range of 0.10 to 0.25 g nitrogen/kg/day corresponds to 11 to 27 ml/kg/day. In obese patients, the dose should be based on the estimated ideal weight. Depending on the patient's requirements, 1000 to 2000 ml may be infused intravenously per 24 hours. Amino acids, Glucose & Electrolytes should be infused slowly, at a rate not exceeding 500 ml in 3 hours, which corresponds to approximately 1.4 to 2.8 ml (30 to 60 drops) per minute. For infants and children, a maximal rate of infusion of 30 ml/kg body weight/day is recommended, with a step-wise increase in the rate of administration during the first week of treatment.