Indications
Amino Acid + Calcium is used to prevent and treat damage caused by faulty or low protein metabolism in chronic renal insufficiency. It goes with a limited protein intake in the diet of 40 g/day (for adults), so in general it is meant for patients with a glomerular filtration rate (GFR) of 25 mL/minutes.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
This tablet lets the body take in essential amino acids while keeping the intake of amino-nitrogen as low as possible. After absorption, the keto- and hydroxy-analogues are transaminated into the matching essential amino acids. They do this by taking nitrogen from non-essential amino acids, so less urea forms because the amino group is used again. This reduces the build-up of uraemic toxins.
Keto and hydroxy acids do not cause hyperfiltration of the residual nephrons. Supplements that contain ketoacids also have a positive effect on renal hyperphosphataemia and secondary hyperparathyroidism, and renal osteodystrophy may improve as well.
When the tablet is used together with a very low protein diet, nitrogen intake can be reduced. At the same time, it helps prevent the harmful effects of too little dietary protein and malnutrition.
Pregnancy & Breastfeeding
There isn't enough data on the use of this Amino Acid + Calcium tablet in pregnant women. Animal studies don't show any direct or indirect harmful effects on pregnancy, on the development of the embryo or foetus, on childbirth, or on development after birth. Even so, caution should be exercised when prescribing it to pregnant women. There is no experience so far with its use during breastfeeding. No case of overdose has been reported.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.