Indications & Uses
TyBlue is used during eye surgery to stain the anterior capsule of the lens, helping the surgeon see it more clearly during the procedure.
Pharmacology
Trypan Blue is a special dye used to selectively stain the front (anterior) capsule of the eye's natural lens. Because the dye does not pass through this capsule, it clearly outlines the anterior lens capsule, setting it apart from the unstained lens cortex and inner lens material underneath.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Injecting Trypan Blue into the eye is done in two steps. First, a fine 26-gauge needle is used to place a small air bubble in the anterior chamber, which keeps the dye from being diluted by the aqueous humor. Next, using a tuberculin syringe, the dye is injected onto the anterior lens capsule. The staining is considered adequate once the capsule has taken up the dye and contracted. If any part remains unstained, an additional drop can be applied until full staining is achieved.
Side Effects
Discoloration of high-water-content hydrogel intraocular lenses may occur. Accidental staining of the back surface of the lens capsule and the front of the vitreous (the gel-like substance filling the eye) can also happen. This staining is usually temporary and typically clears up within a week.
Cautions & Contraindications
Warnings & Precautions
It is recommended that, right after the injection, any excess TyBlue be flushed out of the eye promptly by thoroughly irrigating the anterior chamber.
Contraindications
Trypan Blue should not be used when a dry (non-hydrated), hydrophilic acrylic intraocular lens (IOL) is planned for insertion. The dye can be absorbed by this type of lens and leave it stained.
Pregnancy & Breastfeeding
Pregnancy Category C. No adequate, well-controlled studies have been done in pregnant women, so Trypan Blue should be used during pregnancy only if the potential benefit to the mother justifies the potential risk to the fetus.
Lactation: It is not known whether Trypan Blue passes into human breast milk. Since many drugs do pass into breast milk, caution should be exercised when giving it to a breastfeeding woman.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Pediatric use: Trypan Blue has been shown to be safe and effective in pediatric patients. This is supported by evidence from an adequate and well controlled study in pediatric patients.
Geriatric use: Doctors have not seen any overall differences in safety and effectiveness between elderly and younger patients using Trypan Blue.
Storage
Keep Trypan Blue below 30° C and away from light.
Common questions about Visi Blue 60 mg
What is Visi Blue 60 mg Eye Drops?
Visi Blue 60 mg Eye Drops is a medicine that contains Trypan Blue. It is made by Incepta Pharmaceuticals Ltd. (Dhamrai Unit). It belongs to the Preparations for Ophthalmic diagnosis group of medicines.
What is Visi Blue used for?
TyBlue is used during eye surgery to stain the anterior capsule of the lens, helping the surgeon see it more clearly during the procedure.
What are the side effects of Visi Blue?
Discoloration of high-water-content hydrogel intraocular lenses may occur. Accidental staining of the back surface of the lens capsule and the front of the vitreous (the gel-like substance filling the eye) can also happen.
Can I take Visi Blue during pregnancy or while breastfeeding?
Pregnancy Category C. No adequate, well-controlled studies have been done in pregnant women, so Trypan Blue should be used during pregnancy only if the potential benefit to the mother justifies the potential risk to the fetus. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Visi Blue?
Keep Trypan Blue below 30° C and away from light.
Do I need a prescription for Visi Blue?
Visi Blue is a prescription (Rx) medicine. Take it as your doctor advises.