Indications & Uses
TyBlue is used during eye surgery to stain the anterior capsule of the lens, helping the surgeon see it more clearly during the procedure.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Injecting Trypan Blue into the eye is done in two steps. First, a fine 26-gauge needle is used to place a small air bubble in the anterior chamber, which keeps the dye from being diluted by the aqueous humor. Next, using a tuberculin syringe, the dye is injected onto the anterior lens capsule. The staining is considered adequate once the capsule has taken up the dye and contracted. If any part remains unstained, an additional drop can be applied until full staining is achieved.
Side Effects
Discoloration of high-water-content hydrogel intraocular lenses may occur. Accidental staining of the back surface of the lens capsule and the front of the vitreous (the gel-like substance filling the eye) can also happen. This staining is usually temporary and typically clears up within a week.
Cautions & Contraindications
Warnings & Precautions
It is recommended that, right after the injection, any excess TyBlue be flushed out of the eye promptly by thoroughly irrigating the anterior chamber.
Contraindications
Trypan Blue should not be used when a dry (non-hydrated), hydrophilic acrylic intraocular lens (IOL) is planned for insertion. The dye can be absorbed by this type of lens and leave it stained.