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Other strengths and forms by Square Pharmaceuticals PLC, Pabna
Indications & Uses
Tusca is indicated for:
Pharmacology
Guaiphenesin works as an expectorant. It makes sputum less thick by increasing the volume and water content of the bronchial secretion, so the sputum is easier to bring up. Pseudoephedrine has both direct and indirect sympathomimetic activity and is an effective decongestant for the upper respiratory tract. Compared with ephedrine, it is substantially less potent in causing tachycardia and a rise in systolic blood pressure, and considerably less potent in stimulating the central nervous system. Triporlidine gives symptomatic relief in conditions believed to depend wholly or partly on the triggered release of histamine. It is a potent competitive histamine H1-receptor antagonist of the pyrrolidine class. It also has mild central nervous system depressant properties, which may cause drowsiness.
This syrup is absorbed from the gastrointestinal tract. Guaiphenesin is metabolized and passes out in the urine. Pseudoephedrine is mostly excreted unchanged in the urine, along with small amounts of its hepatic metabolite. Triprolidine is metabolized in the liver and usually leaves the body in the urine as metabolites.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and children over 12 years can take 10 ml (2 teaspoonful) three times a day. For children aged 6 to 12 years, the dose is 5 ml (1 teaspoonful) three times a day. Children aged 2 to 5 years can take 2.5 ml (1/2 teaspoonful) three times a day. For children under 2 years, it's better to get a physician's advice before giving this preparation.
Side Effects
This combination of pseudoephedrine, guaifenesin and triprolidine can depress or excite the central nervous system (CNS). Some people have trouble sleeping, and hallucination has been reported, though rarely. Skin rashes, a fast heartbeat (tachycardia) and a dry mouth, nose and throat have been reported now and then. Men taking pseudoephedrine have occasionally had urinary retention, and an enlarged prostate may well have made it more likely.
Cautions & Contraindications
Warnings & Precautions
This Pseudoephedrine + Guaiphenasine + Triprolidine syrup may cause drowsiness, and it can impair performance in tests of auditory vigilance. It may also affect a patient's ability to drive and to use machinery. So driving and operating machinery should be avoided during treatment with this syrup. Although there are no objective data, people using the syrup should avoid alcohol and other centrally acting sedatives at the same time. Although Pseudoephedrine has virtually no pressor effect in patients with normal blood pressure, the syrup should be used with caution in patients taking antihypertensive agents, tricyclic antidepressants or other sympathomimetic agents such as decongestants, appetite suppressants and amphetamine-like psychostimulants. The effect of a single dose on the blood pressure of these patients should be observed before repeated or unsupervised treatment is recommended. As with other sympathomimetic agents, caution should be exercised in patients with hypertension, heart disease, diabetes, hyperthyroidism, elevated intraocular pressure and prostatic enlargement. The syrup should not be used for persistent or chronic cough, such as occurs with smoking, asthma or emphysema, or where cough is accompanied by excessive secretions, unless a physician directs it.
Contraindications
Don't use this medicine if you are known to be allergic to any of its ingredients. It is also not for people with cardiovascular disease, including hypertension, or lower respiratory symptoms, including asthma. People taking a monoamine oxidase inhibitor (MAOI) should avoid it too.
Pregnancy & Breastfeeding
Pregnancy: Pseudoephedrine, triprolidine and guaiphenesin have been used widely for many years and no obvious harm has been linked to them. Even so, there are no specific data on their use during pregnancy. So take care, and weigh the possible benefit to the mother against any possible hazard to the developing fetus.
Lactation: Guaiphenesin passes into breast milk in small amounts, and no effect is expected on the infant. Pseudoephedrine and triprolidine also pass into breast milk in small amounts, but what this does to a breast fed infant is not known. Be careful with the medicine unless the benefit to the mother outweighs any possible risk to the infant.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Acute toxicity from pseudoephedrine, guaiphenasine and triprolidine can show up as drowsiness, irritability, restlessness, lethargy and dizziness. Some people also get gastrointestinal discomfort, respiratory depression, convulsion, tremor, tachycardia and hypertension.
In case of overdose, take the measures needed to maintain and support respiration and to control convulsion. Gastric lavage may be done if indicated. Catheterization of the bladder may also be necessary.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep this medicine below 25°C and away from light. Don't put it in the refrigerator.
Drug Interactions
Common questions about Tusca 30 mg+100 mg+1.25 mg
What is Tusca 30 mg+100 mg+1.25 mg Syrup?
Tusca 30 mg+100 mg+1.25 mg Syrup is a medicine that contains Pseudoephedrine + Guaiphenasine + Triprolidine. It is made by Square Pharmaceuticals PLC, Pabna. It belongs to the Combined cough expectorants group of medicines.
What is Tusca used for?
Tusca is used for: Cough, Respiratory Tract Infection.
What are the side effects of Tusca?
This combination of pseudoephedrine, guaifenesin and triprolidine can depress or excite the central nervous system (CNS). Some people have trouble sleeping, and hallucination has been reported, though rarely.
Can I take Tusca during pregnancy or while breastfeeding?
Pregnancy: Pseudoephedrine, triprolidine and guaiphenesin have been used widely for many years and no obvious harm has been linked to them. Even so, there are no specific data on their use during pregnancy. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Tusca?
Acute toxicity from pseudoephedrine, guaiphenasine and triprolidine can show up as drowsiness, irritability, restlessness, lethargy and dizziness. Some people also get gastrointestinal discomfort, respiratory depression, convulsion, tremor, tachycardia and hypertension. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Tusca?
Keep this medicine below 25°C and away from light. Don't put it in the refrigerator.
Can I take other medicines with Tusca?
Some medicines can interact with Pseudoephedrine + Guaiphenasine + Triprolidine, for example: Methyldopa. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Tusca?
Tusca is a prescription (Rx) medicine. Take it as your doctor advises.