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These brands contain the same active ingredient (Eltrombopag Olamine). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Tompag
Other strengths and forms by Opsonin Pharma Limited
Indications & Uses
Tompag is indicated for:
Pharmacology
Eltrombopag Olamine is a small molecule thrombopoietin (TPO) receptor agonist. Eltrombopag binds to the transmembrane domain of the human TPO receptor and starts signalling cascades. These signals cause bone marrow progenitor cells to multiply and differentiate, and this finally leads to more platelets being produced.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Eltrombopag tablets are taken by mouth, either without food or with a meal that is low in calcium (<50 mg). For persistent or chronic immune thrombocytopenia, use the lowest dose that gets the platelet count to 50x109/L or above and keeps it there, as needed to reduce the risk of bleeding. Do not exceed 75 mg daily. Adults and pediatric patients 6 years and older with ITP start on 50 mg once daily, except patients of Asian ancestry or those with mild to severe hepatic impairment. Patients of Asian ancestry with ITP start on a reduced dose of 25 mg once daily. Patients with ITP and mild, moderate or severe hepatic impairment also start on a reduced dose of 25 mg once daily. For patients of Asian ancestry with ITP and hepatic impairment, consider starting at a reduced dose of 12.5 mg once daily. Pediatric patients with ITP aged 1 to 5 years start at 25 mg once daily. For thrombocytopenia associated with chronic hepatitis C, the starting dose is 25 mg once daily. Adjust it in 25 mg increments every 2 weeks as necessary to reach the target platelet count required to begin antiviral therapy, and do not exceed 100 mg daily. In first line severe aplastic anemia, start once daily at 2.5 mg/kg for pediatric patients aged 2 to 5 years old, 75 mg for pediatric patients aged 6 to 11 years old, or 150 mg for patients aged 12 years and older. This runs for 6 months, together with standard immunosuppressive therapy. For patients of Asian ancestry or those with mild, moderate or severe hepatic impairment, decrease the initial dose by 50%. The dose regimen is then modified based on platelet counts, ALT or AST elevations and thromboembolic events. In refractory severe aplastic anemia, start at 50 mg once daily. A hematologic response needs dose titration, generally up to 150 mg, and may take up to 16 weeks after starting. For patients of Asian ancestry or those with mild, moderate, or severe hepatic impairment, start at a reduced dose of 25 mg once daily. Adjust the dose in 50 mg increments every 2 weeks as necessary to reach a target platelet count of 50 x 109/L or above. Do not exceed 150 mg per day.
Side Effects
Eltrombopag Olamine most often causes anemia, nausea, fever (pyrexia), raised ALT, cough, tiredness, headache and diarrhea.
Cautions & Contraindications
Warnings & Precautions
In people with chronic hepatitis C, Eltrombopag Olamine taken together with interferon and ribavirin may raise the risk of hepatic decompensation. Liver function should be checked before treatment and during it. There is also a higher risk of death, and of myelodysplastic syndromes progressing to acute myeloid leukemia. Portal vein thrombosis has been reported in people with chronic liver disease who were receiving eltrombopag. Platelet counts need to be checked regularly.
Contraindications
Don't give eltrombopag to anyone who is known to be allergic to eltrombopag or to any other ingredient in the product.
Pregnancy & Breastfeeding
There isn't enough data to judge whether eltrombopag carries any risk of major birth defects, miscarriage, or harm to the mother or the baby. Nobody knows yet if eltrombopag or its metabolites pass into human milk, or what they might do to a breastfed child or to milk production. Because eltrombopag could cause serious adverse reactions in a breastfed child, breastfeeding is not recommended while a woman is on treatment.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Use in children and adolescents: Eltrombopag Olamine hasn't been shown to be safe or effective in children with ITP who are below the age of 1 year. The same is true for children with thrombocytopenia linked to chronic hepatitis C, and for those with refractory severe aplastic anemia. Safety and efficacy have not been established in these groups either.
Overdose
If someone takes too much Eltrombopag Olamine, their platelet counts can rise too far, and that can lead to thrombotic or thromboembolic complications. In an overdose, the doctor may consider giving a preparation containing a metal cation by mouth, such as a calcium, aluminium or magnesium preparation. It binds (chelates) eltrombopag and so limits how much is absorbed.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Eltrombopag Olamine in a cool, dry place where the temperature stays below 25°C, and away from light. Keep it out of the reach of children.
Drug Interactions
Common questions about Tompag 50 mg
What is Tompag 50 mg Tablet?
Tompag 50 mg Tablet is a medicine that contains Eltrombopag Olamine. It is made by Opsonin Pharma Limited. It belongs to the Cytotoxic Chemotherapy group of medicines.
What is Tompag used for?
Tompag is used for: Anemia.
What are the side effects of Tompag?
Eltrombopag Olamine most often causes anemia, nausea, fever (pyrexia), raised ALT, cough, tiredness, headache and diarrhea.
Can I take Tompag during pregnancy or while breastfeeding?
There isn't enough data to judge whether eltrombopag carries any risk of major birth defects, miscarriage, or harm to the mother or the baby. Nobody knows yet if eltrombopag or its metabolites pass into human milk, or what they might do to a breastfed child or to milk production. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Tompag?
If someone takes too much Eltrombopag Olamine, their platelet counts can rise too far, and that can lead to thrombotic or thromboembolic complications. In an overdose, the doctor may consider giving a preparation containing a metal cation by mouth, such as a calcium, aluminium or magnesium preparation. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Tompag?
Keep Eltrombopag Olamine in a cool, dry place where the temperature stays below 25°C, and away from light. Keep it out of the reach of children.
Can I take other medicines with Tompag?
Some medicines can interact with Eltrombopag Olamine, for example: Zinc, Eltrombopag, Iron, Magnesium, Selenium 100 gm/. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Eltropag by Incepta Pharmaceuticals Ltd. has the same ingredient and strength for ৳550.00 per unit, compared with ৳900.00 for Tompag. Ask your doctor or pharmacist before switching.
Do I need a prescription for Tompag?
Tompag is a prescription (Rx) medicine. Take it as your doctor advises.