Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Save on this medicine
Same active ingredient — pay up to 40% less
These brands contain the same active ingredient (Tedizolid Phosphate). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Tezolin is indicated for:
Pharmacology
Tedizolid Phosphate is a prodrug. After it is taken by mouth or given by injection into a vein, phosphatases convert it to Tedizolid, which is the microbiologically active part. With once-daily doses, steady-state concentrations of Tedizolid are reached within approximately three days, with accumulation of approximately 30% (the half-life of Tedizolid is approximately 12 hours).
When taken by mouth on an empty stomach, peak plasma Tedizolid concentrations are reached within approximately 3 hours. The absolute bioavailability is approximately 91%, so no dosage adjustment is needed when switching between the intravenous and oral routes. Tedizolid binds to human plasma proteins at approximately 70 to 90%.
Apart from Tedizolid Phosphate, which accounts for approximately 95% of the total radiocarbon AUC in plasma, there are no other significant circulating metabolites in humans. Tedizolid was not degraded in human liver microsomes, which indicates that Tedizolid Phosphate is unlikely to be a substrate for hepatic CYP450 enzymes. After a single oral dose of 14C-labeled Tedizolid Phosphate under fasted conditions, most of the elimination took place through the liver. About 82% of the radioactive dose was recovered in feces and 18% in urine.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Tedizolid Phosphate is recommended for patients aged 18 years or older. The dose is 200 mg of tedizolid taken once daily for six (6) days by mouth, with or without food. If a patient misses a dose, they should take it as soon as possible, at any time up to 8 hours before the next scheduled dose. If less than 8 hours remain before the next dose, they should wait and take the next dose at its scheduled time.
Use in Children & Adolescents: Safety and effectiveness in paediatric patients below the age of 18 have not been established. No overall differences in pharmacokinetics were observed between elderly subjects and younger subjects.
Side Effects
People treated with Tedizolid Phosphate most often report nausea, headache, diarrhea, vomiting and dizziness. Other side effects have also been reported in patients on Tedizolid Phosphate. These include anemia, palpitations, tachycardia, blurred vision, visual impairment, infusion-related reactions, drug hypersensitivity, insomnia, pruritus, urticaria, dermatitis and hypertension, among others.
Cautions & Contraindications
Warnings & Precautions
Doctors should think about alternative therapies when they treat patients who have neutropenia together with acute bacterial skin and skin structure infection, Clostridium difficile-associated diarrhea, and the risk of drug-resistant bacteria developing. Pharmaceutical precautions: Give Tedizolid Phosphate as an intravenous infusion only. Once the solution has been reconstituted and diluted, look at the intravenous bag for particulate matter before giving it. The infusion is given over a total time of 1 hour. The total time from reconstitution to administration should not go beyond 24 hours, whether the solution is kept at room temperature or in a refrigerator at 2°C to 8°C.
Contraindications
Don't give Tedizolid Phosphate to anyone who is known to be hypersensitive to it, or to any other component in the medicine.
Pregnancy & Breastfeeding
Tedizolid Phosphate is a pregnancy category C medicine. No adequate and well controlled studies have been done in pregnant women. So it should be used during pregnancy only if the possible benefit justifies the possible risk to the fetus. Whether Tedizolid Phosphate passes into human milk is not known.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
If Tedizolid Phosphate is taken in overdose, stop the medicine and give general supportive treatment.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Tedizolid Phosphate in a cool, dry place where the temperature stays below 30°C, and away from light. Keep it out of the reach of children.
Common questions about Tezolin 200 mg
What is Tezolin 200 mg Tablet?
Tezolin 200 mg Tablet is a medicine that contains Tedizolid Phosphate. It is made by Beximco Pharmaceuticals Ltd. It belongs to the Other antibacterial preparation group of medicines.
What is Tezolin used for?
Tezolin is used for: Skin and Soft Tissue Infection.
What are the side effects of Tezolin?
People treated with Tedizolid Phosphate most often report nausea, headache, diarrhea, vomiting and dizziness. Other side effects have also been reported in patients on Tedizolid Phosphate.
Can I take Tezolin during pregnancy or while breastfeeding?
Tedizolid Phosphate is a pregnancy category C medicine. No adequate and well controlled studies have been done in pregnant women. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Tezolin?
If Tedizolid Phosphate is taken in overdose, stop the medicine and give general supportive treatment. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Tezolin?
Keep Tedizolid Phosphate in a cool, dry place where the temperature stays below 30°C, and away from light. Keep it out of the reach of children.
Is there a cheaper medicine with the same ingredient?
Nexolid by Renata PLC has the same ingredient and strength for ৳300.00 per unit, compared with ৳500.00 for Tezolin. Ask your doctor or pharmacist before switching.
Do I need a prescription for Tezolin?
Tezolin is a prescription (Rx) medicine. Take it as your doctor advises.