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Other brands with the same active ingredient
These brands contain the same active ingredient (Trifluoperazine). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Telazine
Other strengths and forms by Eskayef Pharmaceuticals Ltd. Mirpur.
Indications & Uses
Telazine is indicated for:
Pharmacology
Trifluoperazine belongs to the phenothiazine group of medicines, so it has a number of effects in the body. Some of these are the reason it works, and some are side effects. The most important action of phenothiazines is blocking dopamine receptors in the central nervous system (CNS). It is thought that this blocking in the limbic system and related parts of the cerebral cortex is what gives phenothiazines their antipsychotic effect. In the medullary chemoreceptor trigger zone, the same action seems to be responsible for their antiemetic effect, which is the ability to stop nausea and vomiting.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Schizophrenia and other psychoses: Adults and children over 12 years: the recommended starting dose is 2 to 5 mg twice daily, increased by 5 mg daily after 1 week, then at intervals of 3 days according to response. Children (6 to 12 years): dosage should be adjusted to the weight of the child and the severity of the symptoms. The starting dosage is 1 mg twice daily. Dosage may be increased gradually until symptoms are controlled or until side effects become troublesome, though it is usually not necessary to exceed 15 mg daily. Elderly: reduce the initial dose by at least half. Short term management of severe anxiety: Adults and children over 12 years: 1 to 2 mg twice daily, increased if necessary to 6 mg daily. Children (3 to 5 years): 1 mg daily. Children (6 to 12 years): up to 4 mg daily in divided doses. Elderly: reduce the initial dose by at least half. Antiemetic: Adults: 2 to 4 mg daily in divided doses, maximum 6 mg daily. Children 3 to 5 years: up to 1 mg daily; 6 to 12 years: up to 4 mg daily.
Side Effects
Common side effects include transient restlessness, dystonias, or symptoms resembling parkinsonism. Other CNS reactions include drowsiness, dizziness, fatigue, blurred vision, and seizures. Apart from these CNS effects, peripheral oedema, blood dyscrasias, and jaundice may occasionally occur. Tachycardia, constipation, urinary hesitancy and retention, and hyperpyrexia have been reported very rarely.
Cautions & Contraindications
Warnings & Precautions
Care should be taken when treating older patients, starting with a reduced initial dose. This group can be especially sensitive to the drug's effects, particularly extrapyramidal symptoms and drops in blood pressure. Similarly, caution is advised in patients with cardiovascular disease, including arrhythmias, and those with angina pectoris should also be treated carefully.
Contraindications
Trifluoperazine should not be given to patients who are comatose, who have a known blood disorder or liver damage, or who are hypersensitive to trifluoperazine or other phenothiazine drugs.
Pregnancy & Breastfeeding
Pregnancy: The safety of trifluoperazine in pregnancy has not been established. For this reason, it is not recommended for pregnant patients unless, in the physician's judgement, its use is essential, and the potential benefits clearly outweigh the possible risks. There have been reports of prolonged jaundice, extrapyramidal signs, and increased or decreased reflexes in newborn infants whose mothers received phenothiazines during pregnancy.
Breastfeeding: There is not enough human data available on the use of this medicine during breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
In an overdose of Trifluoperazine, the signs and symptoms are mostly extrapyramidal, and low blood pressure (hypotension) may also occur. Treatment is gastric lavage along with supportive and symptomatic care. Don't induce vomiting.
Extrapyramidal symptoms can be treated with an anticholinergic, antiparkinsonism drug. Hypotension is treated with fluid replacement. If it is severe or persistent, noradrenaline may be considered. Adrenaline is contraindicated.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Trifluoperazine at room temperature, between 15 and 30° C. Keep it away from light and moisture.
Drug Interactions
Common questions about Telazine 1 mg
What is Telazine 1 mg Tablet?
Telazine 1 mg Tablet is a medicine that contains Trifluoperazine. It is made by Eskayef Pharmaceuticals Ltd. Mirpur. It belongs to the Phenothiazine drugs group of medicines.
What is Telazine used for?
Telazine is used for: Nausea and Vomiting, Depression, Anxiety, Schizophrenia.
What are the side effects of Telazine?
Common side effects include transient restlessness, dystonias, or symptoms resembling parkinsonism. Other CNS reactions include drowsiness, dizziness, fatigue, blurred vision, and seizures.
Can I take Telazine during pregnancy or while breastfeeding?
Pregnancy: The safety of trifluoperazine in pregnancy has not been established. For this reason, it is not recommended for pregnant patients unless, in the physician's judgement, its use is essential, and the potential benefits clearly outweigh the possible risks. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Telazine?
In an overdose of Trifluoperazine, the signs and symptoms are mostly extrapyramidal, and low blood pressure (hypotension) may also occur. Treatment is gastric lavage along with supportive and symptomatic care. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Telazine?
Store Trifluoperazine at room temperature, between 15 and 30° C. Keep it away from light and moisture.
Can I take other medicines with Telazine?
Some medicines can interact with Trifluoperazine, for example: Propranolol Hydrochloride. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Telazine?
Telazine is a prescription (Rx) medicine. Take it as your doctor advises.