Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Save on this medicine
Same active ingredient — pay up to 14% less
These brands contain the same active ingredient (Sulphadoxine + Pyrimethamine). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Sulfamin
Other strengths and forms by Jayson Pharmaceuticals Ltd.
Indications & Uses
Sulfamin is indicated for:
Pharmacology
Sulphadoxine + Pyrimethamine is an antimalarial that works through synergism. Each component given alone gives a weaker result, even at higher doses, than the two do together.
The combination is also effective against strains that are resistant to other antimalarial medicines, and the risk of resistance developing with it is minimal. It is an extremely long acting medicine. It attacks the different development stages of the parasite and reaches an effective concentration with a single dose. That single dose protects for about four weeks. Sulphadoxine + Pyrimethamine can be used together with other antimalarial drugs and with antibiotics, and it does not influence the action of antidiabetic agents.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Sulphadoxine + Pyrimethamine is given as a single dose for curative treatment of malaria. Adults take 2 to 3 tablets. For children under 4 years the dose is ½ tablets, for 4 to 8 years it is 1 tablet, and for 9 to 14 years it is 2 tablets. In severe cases, Sulphadoxine & Pyrimethamine can be combined with quinine to good effect.
For suppressive or prophylactic use, the dose below should be taken all at one time. For semi-immune subjects, the dose is taken once every four weeks. Adults take 2 to 3 tablets, children under 4 years take ½ tablets, children aged 4 to 8 years take 1 tablet, and children aged 9 to 14 years take 2 tablets. For non-immune subjects, the dose is taken once every two weeks. Adults take 2 tablets, children under 4 years take 1½ tablets, children aged 4 to 8 years take 1 tablet, and children aged 9 to 14 years take 1½ tablets.
For malaria prophylaxis, take the first dose of Sulphadoxine & Pyrimethamine one or two days before leaving for an endemic area, so that tolerance is protected. Keep taking it at the same dosage during the stay and for four weeks after returning, or as the physician prescribes.
Side Effects
Sulphadoxine and Pyrimethamine is well tolerated when taken at the recommended dose. The main side effects are listed below. Skin reactions: drug rash, pruritus and slight hair loss have been seen. Gastro-intestinal reactions: a feeling of fullness, nausea, stomatitis, and rarely vomiting. Haematological reactions: in rare cases, leukopenia, thrombocytopenia and megaloblastic anemia have been observed. Other reactions: fatigue, headache, fever and polyneuritis may occasionally occur.
Cautions & Contraindications
Warnings & Precautions
Take extra care with Sulphadoxine + Pyrimethamine if the patient has impaired kidney or liver function, folate deficiency, severe allergy or bronchial asthma, or G6PD deficiency. Care is also needed in pregnancy. Take the medicine with plenty of water to prevent crystalluria. Avoid too much exposure to the sun. Stop the medicine at the first sign of a rash, and stop it too if signs of folic acid deficiency develop. When it is given for more than 3 months, the patient needs regular CBC monitoring and LFT, and the urine should be checked for crystalluria. Take it with food to reduce stomach and bowel effects such as anorexia and vomiting.
Contraindications
Repeated use of Sulphadoxine + Pyrimethamine as a preventive (prophylaxis) is contraindicated in people with severe renal insufficiency, marked liver parenchymal damage or blood dyscrasias. If any mucocutaneous signs or symptoms appear, such as pruritus, erythema, rash, orogenital lesions or pharyngitis, stop the treatment immediately.
Pregnancy & Breastfeeding
Sulphadoxine & Pyrimethamine must not be used during pregnancy. It is also contraindicated in premature and newborn infants during the first weeks of life, and in anyone who cannot tolerate sulfonamides. If pregnancy can't be excluded, the possible risks should be weighed against the benefit of the treatment. Both Pyrimethamine and Sulphadoxine pass into the mother's breast milk, so a nursing mother should not take this preparation.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Sulphadoxine + Pyrimethamine below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Sulfamin 500 mg+25 mg
What is Sulfamin 500 mg+25 mg Tablet?
Sulfamin 500 mg+25 mg Tablet is a medicine that contains Sulphadoxine + Pyrimethamine. It is made by Jayson Pharmaceuticals Ltd. It belongs to the Anti-malarial drugs group of medicines.
What is Sulfamin used for?
Sulfamin is used for: Malaria.
What are the side effects of Sulfamin?
Sulphadoxine and Pyrimethamine is well tolerated when taken at the recommended dose. The main side effects are listed below.
Can I take Sulfamin during pregnancy or while breastfeeding?
Sulphadoxine & Pyrimethamine must not be used during pregnancy. It is also contraindicated in premature and newborn infants during the first weeks of life, and in anyone who cannot tolerate sulfonamides. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Sulfamin?
Store Sulphadoxine + Pyrimethamine below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Sulfamin?
Some medicines can interact with Sulphadoxine + Pyrimethamine, for example: Methotrexate, Folate, Folic Acid. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Malason by Hudson Pharmaceuticals Ltd. has the same ingredient and strength for ৳3.80 per unit, compared with ৳4.43 for Sulfamin. Ask your doctor or pharmacist before switching.
Do I need a prescription for Sulfamin?
Sulfamin is a prescription (Rx) medicine. Take it as your doctor advises.