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Same active ingredient — pay up to 73% less
These brands contain the same active ingredient (Rosuvastatin Calcium). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Rovex
Other strengths and forms by Orion Pharma Ltd.
Indications & Uses
Rovex is indicated for:
Pharmacology
Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase. This enzyme sets the pace for the conversion of 3-hydroxy-3-methyl glutaryl coenzyme A to mevalonate, which is a precursor of cholesterol. Rosuvastatin changes blood lipids in two ways. First, it raises the number of LDL receptors on the surface of liver cells, so the liver takes up and breaks down more LDL. Second, it blocks the liver's synthesis of VLDL, and this lowers the total number of VLDL and LDL particles.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Heterozygous Familial Hypercholesterolemia in Pediatric Patients (10 to 17 years of age): The usual dose range of Rosuvastatin is 5 to 20 mg a day, and the maximum recommended dose is 20 mg a day (doses above 20 mg have not been studied in this patient group). Doses should be individualized according to the recommended goal of therapy. Adjustments should be made at intervals of 4 weeks or more.
Very High Cholesterol and High Risk of MI or Stroke: 40 mg once daily.
Homozygous Familial Hypercholesterolemia: The recommended starting dose of Rosuvastatin is 20 mg once daily. Response to therapy should be estimated from preapheresis LDL-C levels.
Dosage in Asian Patients: Starting Rosuvastatin at 5 mg once daily should be considered for Asian patients.
Use with Cyclosporine, Lopinavir/Ritonavir or Atazanavir/Ritonavir: In patients taking Cyclosporine, the dose of Rosuvastatin should be limited to 5 mg once daily. In patients taking Lopinavir and Ritonavir together, or Atazanavir and Ritonavir together, the dose of Rosuvastatin should be limited to 10 mg once daily.
Concomitant Lipid-Lowering Therapy: The risk of skeletal muscle effects may be higher when Rosuvastatin is used with Niacin or Fenofibrate, so a lower Rosuvastatin dose should be considered in this setting. Combination with Gemfibrozil should be avoided because it raises Rosuvastatin exposure. If Rosuvastatin is used with Gemfibrozil, the dose of Rosuvastatin should be limited to 10 mg once daily.
Dosage in Patients with Severe Renal Impairment: For patients with severe renal impairment (ClCr<30 mL/min/1.73 m²) who are not on hemodialysis, Rosuvastatin should be started at 5 mg once daily and should not go above 10 mg once daily.
Side Effects
RVN is generally well tolerated. The side effects most often thought to be related to RVN were headache, myalgia, constipation, asthenia, abdominal pain and nausea.
Cautions & Contraindications
Warnings & Precautions
Take care when prescribing RVN (rosuvastatin) to patients who already have a higher chance of myopathy, for example age >65 years, hypothyroidism that isn't adequately treated, or renal impairment. The risk of myopathy with RVN can go up if the patient is also taking some other lipid-lowering therapies (Fibrates or Niacin), Gemfibrozil, Cyclosporine, Lopinavir/Ritonavir, or Atazanavir/Ritonavir. Stop RVN therapy if creatinine kinase levels are markedly raised, or if myopathy is diagnosed or suspected. RVN should also be withheld for a time in any patient with an acute, serious condition that suggests myopathy or makes renal failure secondary to rhabdomyolysis more likely. Examples are sepsis, hypotension, dehydration, major surgery, trauma, severe metabolic, endocrine and electrolyte disorders, or uncontrolled seizures. Liver enzyme tests are recommended before starting therapy and again at 12 weeks after the start and after any increase in dose. After that, they should be repeated periodically (e.g., semiannually).
Contraindications
Rosuvastatin should not be used if the person has a known hypersensitivity to any of the components of the product. It is also contraindicated in liver disease, which may include unexplained persistent elevations in hepatic transaminase levels. Pregnant women and women who may become pregnant should not take it, and nor should nursing mothers.
Pregnancy & Breastfeeding
Rosuvastatin should be given to women who could become pregnant only when they are highly unlikely to conceive and have been told about the possible hazards. If a woman becomes pregnant while she is taking rosuvastatin, the treatment should be stopped immediately. It isn't known whether rosuvastatin passes into human milk, but a small amount of another medicine in this class does pass into breast milk.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
There is no specific treatment for a Rosuvastatin Calcium overdose. The patient should be treated for the symptoms as they appear, and supportive measures should be started as needed. Hemodialysis does not significantly enhance the clearance of Rosuvastatin Calcium.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Rosuvastatin Calcium below 30°C, away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Rovex 10 mg
What is Rovex 10 mg Tablet?
Rovex 10 mg Tablet is a medicine that contains Rosuvastatin Calcium. It is made by Orion Pharma Ltd. It belongs to the Other Anti-anginal & Anti-ischaemic drugs group of medicines.
What is Rovex used for?
Rovex is used for: Myocardial Infarction, Hyperlipidemia, Stroke.
What are the side effects of Rovex?
RVN is generally well tolerated. The side effects most often thought to be related to RVN were headache, myalgia, constipation, asthenia, abdominal pain and nausea.
Can I take Rovex during pregnancy or while breastfeeding?
Rosuvastatin should be given to women who could become pregnant only when they are highly unlikely to conceive and have been told about the possible hazards. If a woman becomes pregnant while she is taking rosuvastatin, the treatment should be stopped immediately. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Rovex?
There is no specific treatment for a Rosuvastatin Calcium overdose. The patient should be treated for the symptoms as they appear, and supportive measures should be started as needed. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Rovex?
Store Rosuvastatin Calcium below 30°C, away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Rovex?
Some medicines can interact with Rosuvastatin Calcium, for example: Cyclosporine, Niacin, Atazanavir, Ritonavir. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
RTV by Delta Pharma PLC. has the same ingredient and strength for ৳6.00 per unit, compared with ৳22.00 for Rovex. Ask your doctor or pharmacist before switching.
Do I need a prescription for Rovex?
Rovex is a prescription (Rx) medicine. Take it as your doctor advises.