Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Polydex-N
Rx1 mg+3500 IU+6000 IU • Ophthalmic Solution
Indications & Uses
Dexamethasone + Neomycin Sulphate + Polymyxin B Sulphate is used for a short course of treatment in eye conditions that respond to steroids, where an antibiotic is also needed to prevent infection. Fungal and viral disease must be ruled out before it is given.
Pharmacology
Dexamethasone is a corticosteroid. It suppresses the inflammatory response to many different agents, and it probably delays or slows healing. A corticosteroid may also weaken the body's defence against infection, so an antimicrobial medicine may be used alongside it when this effect is considered clinically significant in a particular case. In this combination of dexamethasone, neomycin sulphate and polymyxin B sulphate, the anti-infective part is there to act against the specific organisms that are susceptible to it.
Neomycin sulphate is considered active against these microorganisms: Staphylococcus aureus, Corynebacterium diphtheriae, Streptococcus Viridans, Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Aerobacter aerogenes and Haemophilus influenzae. Polymyxin B sulphate is considered active against these: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Klebsiella pneumoniae and Koch-Weeks bacillus.
Once a decision has been made to give both a corticosteroid and an antimicrobial, using them together in one preparation has some advantages. Patients are more likely to follow the treatment, and it is more convenient for them. The appropriate dose of both drugs is assured, and so is the compatibility of the ingredients when both types of drug are in the same formulation. In particular, the correct volume of the drug is delivered and retained.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Put one or two drops in each affected eye, up to six times a day, or more often if needed. For severe infections, you may need one or two drops every 15 to 20 minutes at the start, then cut down how often you put them in as the infection comes under control. Or use it as directed by a registered physician.
Side Effects
Allergic sensitisation is the reaction seen most often with this combination of Dexamethasone, Neomycin Sulphate and Polymyxin B Sulphate. The steroid part can cause other problems too. These are a rise in intraocular pressure (IOP), which may lead to damage of the optic nerve, posterior subcapsular cataract formation, and delayed wound healing.
Cautions & Contraindications
Warnings & Precautions
Don't use this preparation for long periods, because it can cause skin sensitisation and let resistant organisms emerge. It can also lead to steroid glaucoma and cataract formation, so the intraocular pressure and the lens must be checked often while the preparation is being used.
Pregnancy & Breastfeeding
Dexamethasone + Neomycin Sulphate + Polymyxin B Sulphate is a Pregnancy Category C medicine. Animal reproduction studies have shown an adverse effect on the fetus, and there are no adequate and well-controlled studies in humans. Even so, the potential benefits may justify using the medicine in pregnant women despite the possible risks.
It is not known whether the medicine passes into breast milk. Systemic absorption is minimal when it is used in the eye.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store this medicine below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Common questions about Polydex-N 1 mg+3500 IU+6000 IU
What is Polydex-N 1 mg+3500 IU+6000 IU Ophthalmic Solution?
Polydex-N 1 mg+3500 IU+6000 IU Ophthalmic Solution is a medicine that contains Dexamethasone + Neomycin Sulphate + Polymyxin B Sulphate. It is made by Aristopharma Limited. It belongs to the Ophthalmic steroid - antibiotic combined preparations group of medicines.
What is Polydex-N used for?
Dexamethasone + Neomycin Sulphate + Polymyxin B Sulphate is used for a short course of treatment in eye conditions that respond to steroids, where an antibiotic is also needed to prevent infection. Fungal and viral disease must be ruled out before it is given.
What are the side effects of Polydex-N?
Allergic sensitisation is the reaction seen most often with this combination of Dexamethasone, Neomycin Sulphate and Polymyxin B Sulphate. The steroid part can cause other problems too.
Can I take Polydex-N during pregnancy or while breastfeeding?
Dexamethasone + Neomycin Sulphate + Polymyxin B Sulphate is a Pregnancy Category C medicine. Animal reproduction studies have shown an adverse effect on the fetus, and there are no adequate and well-controlled studies in humans. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Polydex-N?
Store this medicine below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Do I need a prescription for Polydex-N?
Polydex-N is a prescription (Rx) medicine. Take it as your doctor advises.