Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Nicor is indicated for:
Pharmacology
Nicorandil works by opening potassium channels, which relaxes the arterioles and the large coronary arteries. It also activates guanylate cyclase, an action that widens the veins. Together, these effects ease the heart's workload by lowering both preload and afterload, while also improving blood flow through the coronary arteries.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The usual dose for adults with nicorandil is 10 to 20 mg twice daily. Most people start on 10 mg twice daily, preferably once in the morning and once in the evening. The dose can then be raised, depending on the patient's needs, response and how well they tolerate it, up to 40 mg twice daily if necessary. Some people who are especially prone to headache may begin on a lower dose of 5 mg twice daily.
For elderly patients there are no special dosage requirements, but as with all medicines, the lowest effective dose should be used. Doctors usually start older patients on a low dose and give nicorandil with care.
Nicorandil is not recommended for children.
Nicorandil should be used with caution in patients with serious hepatic dysfunction. Hepatic impairment may mean the dose needs to be reduced.
Side Effects
Headache is common, especially when starting treatment, but it usually settles with continued use. Nicorandil can also widen skin blood vessels, causing flushing; some people notice nausea, vomiting, dizziness, or weakness. Mouth ulcers and muscle aches occur rarely. At high doses, blood pressure may drop and/or heart rate may rise. Angioedema (swelling beneath the skin) has also been reported.
Cautions & Contraindications
Warnings & Precautions
Hypovolaemia, low systolic BP, acute pulmonary oedema, or pregnancy may rule out use. May affect the ability to drive or operate machinery.
Contraindications
Nicorandil tablets should not be used by anyone who has shown hypersensitivity to Nicorandil. The medicine is also not suitable for patients in cardiogenic shock, for those with acute myocardial infarction accompanied by acute left ventricular failure and low filling pressures, or for patients with hypotension. It should not be taken together with phosphodiesterase-5 inhibitors, since combining the two can cause a serious drop in blood pressure. Warnings and precautions: Nicorandil should be used cautiously in patients who may have depleted blood volume or who have a low systolic blood pressure (below 100 mm Hg). Its use should be avoided altogether in patients with cardiogenic shock, or with acute myocardial infarction accompanied by acute left ventricular failure and low filling pressures. If mouth ulceration, stomatitis, or persistent or severe ulceration of the cheek lining develops, Nicorandil should be stopped and suitable treatment given. Patients with glaucoma should use Nicorandil with caution. Combining Nicorandil with other vasodilators, tricyclic antidepressants, or alcohol can increase their blood-pressure-lowering effect. Because therapeutic doses of Nicorandil can themselves lower blood pressure in hypertensive patients, it should, like other antianginal medicines, be prescribed carefully alongside antihypertensive drugs. Animal studies on mutagenicity and carcinogenicity have not shown any harmful effect of Nicorandil under the experimental conditions tested.
Pregnancy & Breastfeeding
During pregnancy, animal studies have not pointed to any harm to the unborn baby from Nicorandil, but the medicine has not been studied in pregnant women. If it is used during pregnancy, the expected benefit needs to be weighed against any possible risk. It is not known whether Nicorandil passes into human breast milk, so it should be used with caution in breastfeeding mothers.
Drug interactions: Studies in animals and humans have not shown a pharmacological or pharmacokinetic interaction between Nicorandil and beta-blockers, calcium channel blockers, digoxin, a digoxin and furosemide combination, rifampicin, or cimetidine. Even so, it cannot be ruled out that Nicorandil may add to the effect of other vasodilators, tricyclic antidepressants and blood pressure lowering drugs taken at the same time, particularly when combined with alcohol.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
If someone takes too much Nicorandil, the likely effect is widening of the blood vessels in the arms and legs (peripheral vasodilation). This brings a fall in blood pressure and a fast heartbeat as the body reacts to it (reflex tachycardia). Heart function should be monitored, and general supportive measures should be given. If these don't work, the volume of blood plasma in circulation should be raised by replacing fluid. In life-threatening situations, vasopressors should be considered.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Nicorandil in a cool, dry place and away from light.
Drug Interactions
Common questions about Nicor 10 mg
What is Nicor 10 mg Tablet?
Nicor 10 mg Tablet is a medicine that contains Nicorandil. It is made by Orion Pharma Ltd. It belongs to the Potassium-channel activator group of medicines.
What is Nicor used for?
Nicor is used for: Angina Pectoris.
What are the side effects of Nicor?
Headache is common, especially when starting treatment, but it usually settles with continued use. Nicorandil can also widen skin blood vessels, causing flushing; some people notice nausea, vomiting, dizziness, or weakness.
Can I take Nicor during pregnancy or while breastfeeding?
During pregnancy, animal studies have not pointed to any harm to the unborn baby from Nicorandil, but the medicine has not been studied in pregnant women. If it is used during pregnancy, the expected benefit needs to be weighed against any possible risk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Nicor?
If someone takes too much Nicorandil, the likely effect is widening of the blood vessels in the arms and legs (peripheral vasodilation). This brings a fall in blood pressure and a fast heartbeat as the body reacts to it (reflex tachycardia). In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Nicor?
Keep Nicorandil in a cool, dry place and away from light.
Can I take other medicines with Nicor?
Some medicines can interact with Nicorandil, for example: Ketoprofen, Rifampicin, Digoxin, Cimetidine, Furosemide. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Nicor is already among the lowest-priced brands of Nicorandil at this strength.
Do I need a prescription for Nicor?
Nicor is a prescription (Rx) medicine. Take it as your doctor advises.