Pricing
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All price changes →Indications & Uses
Methovate-R is indicated for:
Pharmacology
Betamethasone is a corticosteroid with mainly glucocorticoid activity. It induces phospholipase A2 inhibitory lipase (lipocortins), and this in turn inhibits the release of arachidonic acid step by step. The result is less formation, release and activity of prostaglandins, leukotrienes and other inflammatory mediators. Phenylephrine is a sympathomimetic. Its effects are mainly direct, on alpha-adrenergic receptors, and its beta-adrenergic activity is weak. It causes vasoconstriction of the arterioles of the nasal mucosa and conjunctiva. It also activates the dilator muscle of the pupil, which makes the pupil contract, and it produces vasoconstriction of arterioles in the body and systemic arterial vasoconstriction. Lidocaine alters signal conduction in neurons. It blocks the fast voltage-gated Na+ channels in the neuronal cell membrane, which are responsible for signal propagation. With sufficient blockage, the membrane of the postsynaptic neuron will not depolarize, so it fails to transmit an action potential.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Limit a course of treatment with this betamethasone, phenylephrine and lignocaine ointment to 7 days. At the start, apply a small amount two or three times a day, and use the applicator if the ointment has to go inside. Once the inflammation begins to settle, applying it once a day is enough in most cases. Otherwise, follow the doctor's directions.
Side Effects
Some people may show signs of hypersensitivity. If treatment with highly active corticosteroid preparations goes on for a long time and is used intensively, it may cause local atrophic changes in the skin.
Cautions & Contraindications
Warnings & Precautions
Try to avoid long-term continuous use of this medicine where you can, especially in infants and children, because adrenal suppression can occur.
Contraindications
Don't use this ointment if the person has a primary viral infection of the skin, such as herpes simplex or chickenpox. It also shouldn't be used by anyone who is hypersensitive to any of its components. The ointment is not indicated for skin lesions that are primarily infected with fungi (for example candidiasis or tinea) or with bacteria (for example impetigo).
Pregnancy & Breastfeeding
Human pregnancy safety evidence for this medicine is not enough.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store this medicine below 30°C and keep it away from light and moisture. Keep it out of the reach of children.
Common questions about Methovate-R 0.05%+0.1%+2.5%
What is Methovate-R 0.05%+0.1%+2.5% Rectal Ointment?
Methovate-R 0.05%+0.1%+2.5% Rectal Ointment is a medicine that contains Betamethasone + Phenylephrine + Lignocaine. It is made by G. A. Company Ltd. It belongs to the 4-Quinolone preparations group of medicines.
What is Methovate-R used for?
Methovate-R is used for: Pain, Hemorrhoids, Urticaria.
What are the side effects of Methovate-R?
Some people may show signs of hypersensitivity. If treatment with highly active corticosteroid preparations goes on for a long time and is used intensively, it may cause local atrophic changes in the skin.
Can I take Methovate-R during pregnancy or while breastfeeding?
Human pregnancy safety evidence for this medicine is not enough. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Methovate-R?
Store this medicine below 30°C and keep it away from light and moisture. Keep it out of the reach of children.
Do I need a prescription for Methovate-R?
Methovate-R is a prescription (Rx) medicine. Take it as your doctor advises.