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Same active ingredient — pay up to 60% less
These brands contain the same active ingredient (Trimetazidine Dihydrochloride). Same strength and form. Confirm the switch with your doctor or pharmacist.
Metacard MR
Rx35 mg • Tablet (Modified Release)
Indications & Uses
Metacard MR is indicated for:
Pharmacology
Trimetazidine Dihydrochloride was the first 3-keto acyl CoA thiolase inhibitor (KAT) developed, a metabolic anti-ischaemic agent shown to benefit all coronary patients. It works by inhibiting the 3-keto acyl CoA thiolase enzyme, which blocks the fatty acid pathway and shifts the heart's energy production toward the glucose pathway instead. Because the glucose pathway generates energy more efficiently, the same amount of oxygen yields more energy, helping the heart work more actively. The aerobic breakdown of glucose also halts the buildup of lactic acid, which helps prevent angina pectoris.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The recommended dose of Trimetazidine Dihydrochloride is 35 mg twice daily, or alternatively 20 mg three times a day with meals. Treatment benefit should be reviewed after three months, and Trimetazidine should be stopped if no improvement is seen.
Side Effects
Vastadin MR is safe and well tolerated. Common side effects seen with Vastadin MR include dizziness, headache, abdominal pain, diarrhoea, dyspepsia, nausea, vomiting, rash, pruritus, urticaria and asthenia.
Cautions & Contraindications
Warnings & Precautions
Vastadin MR does not relieve an angina attack that is already underway, and it should not be relied on as the first treatment when angina is unstable. It is likewise not used to treat a heart attack (myocardial infarction).
Contraindications
Trimetazidine should not be used by anyone who is hypersensitive to the active substance or to any of the excipients in the formulation. It is also unsuitable for patients with Parkinson's disease, parkinsonian symptoms, tremors, restless legs syndrome, or severe renal impairment.
Pregnancy & Breastfeeding
There is no data on the use of trimetazidine in pregnant women. Animal studies have not shown any direct or indirect harmful effects on reproduction. Even so, as a precaution, it is better to avoid trimetazidine during pregnancy.
It is not known whether trimetazidine passes into human breast milk, and a risk to newborns and infants cannot be ruled out. For that reason, trimetazidine should not be taken while breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Trimetazidine Dihydrochloride in a dry place, away from light and heat. Keep it out of the reach of children.
Drug Interactions
Common questions about Metacard MR 35 mg
What is Metacard MR 35 mg Tablet (Modified Release)?
Metacard MR 35 mg Tablet (Modified Release) is a medicine that contains Trimetazidine Dihydrochloride. It is made by Aristopharma Limited. It belongs to the Other Anti-anginal & Anti-ischaemic drugs group of medicines.
What is Metacard MR used for?
Metacard MR is used for: Angina Pectoris.
What are the side effects of Metacard MR?
Vastadin MR is safe and well tolerated. Common side effects seen with Vastadin MR include dizziness, headache, abdominal pain, diarrhoea, dyspepsia, nausea, vomiting, rash, pruritus, urticaria and asthenia.
Can I take Metacard MR during pregnancy or while breastfeeding?
There is no data on the use of trimetazidine in pregnant women. Animal studies have not shown any direct or indirect harmful effects on reproduction. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Metacard MR?
Store Trimetazidine Dihydrochloride in a dry place, away from light and heat. Keep it out of the reach of children.
Can I take other medicines with Metacard MR?
Some medicines can interact with Trimetazidine Dihydrochloride, for example: Heparin Sodium. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Zivent MR by Ibn Sina Pharmaceutical Ind. Ltd. has the same ingredient and strength for ৳4.00 per unit, compared with ৳10.00 for Metacard MR. Ask your doctor or pharmacist before switching.
Do I need a prescription for Metacard MR?
Metacard MR is a prescription (Rx) medicine. Take it as your doctor advises.