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Same active ingredient — pay up to 29% less
These brands contain the same active ingredient (Meclizine + Pyridoxine). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Mecliz Plus
Other strengths and forms by NIPRO JMI Pharma Limited
Indications & Uses
Mecliz Plus is indicated for:
Pharmacology
Meclizine is a piperazine-derivative antihistamine, and it is used as an antiemetic. It has antiemetic, anticholinergic and antihistaminic properties, and it reduces the sensitivity of the labyrinthine apparatus. The action may be mediated through nerve pathways to the vomiting center (VC) from the chemoreceptor trigger zone (CTZ), through peripheral nerve pathways, through the VC itself, or through other CNS centers.
Pyridoxine is vitamin B-6. It has been added to enhance the anti-emetic effects of meclizine and as a dietary supplement.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and children aged 12 years and over can take Meclizine + Pyridoxine as follows.
For nausea and vomiting, the dose is 25-50 mg daily, or as directed by a physician.
For motion sickness, take a first dose of 25-50 mg, 1 hour before travel. The dose can be repeated every 24 hours for as long as the journey lasts.
For radiation sickness, the dose is 50 mg, given 2-12 hours before radiation treatment.
For vertigo, the dose is 25-100 mg daily, divided into smaller doses through the day.
To prevent nausea and vomiting linked with the emergency contraceptive pill (ECP), take 25-50 mg 1 hour before the first ECP dose. If needed, repeat it after 24 hours.
Safety and efficacy in children under 12 years of age have not been established.
Side Effects
Meclizine with pyridoxine can cause drowsiness and dry mouth. Blurred vision has also been reported, but only rarely.
Cautions & Contraindications
Warnings & Precautions
Meclizine Hydrochloride can affect a person's ability to do things that need mental alertness or good physical coordination, such as operating machinery or driving a motor vehicle, so patients should be warned about this. Alcoholic drinks should be avoided while taking Meclizine + Pyridoxine. Because of its possible anticholinergic action, Meclizine + Pyridoxine should be used with caution in patients with asthma, glaucoma or an enlarged prostate gland.
Contraindications
Patients who are hypersensitive to Meclizine Hydrochloride or Pyridoxine Hydrochloride should not take this combination medicine.
Pregnancy & Breastfeeding
Meclizine with Pyridoxine is Pregnancy Category B. Large-scale human studies have not shown any harmful effects on the baby. Based on the data available, it has been suggested that meclizine carries the lowest risk of causing birth defects, which makes it the first-choice medicine for nausea and vomiting in pregnancy. For a nursing mother, though, safety has not been established.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Symptoms: extreme excitability, seizures, drowsiness and hallucinations.
Treatment: appropriate supportive and symptomatic treatment. Dialysis may be considered.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Meclizine + Pyridoxine below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Mecliz Plus 25 mg+50 mg
What is Mecliz Plus 25 mg+50 mg Tablet?
Mecliz Plus 25 mg+50 mg Tablet is a medicine that contains Meclizine + Pyridoxine. It is made by NIPRO JMI Pharma Limited. It belongs to the Anti-emetic drugs group of medicines.
What is Mecliz Plus used for?
Mecliz Plus is used for: Vertigo, Nausea and Vomiting.
What are the side effects of Mecliz Plus?
Meclizine with pyridoxine can cause drowsiness and dry mouth. Blurred vision has also been reported, but only rarely.
Can I take Mecliz Plus during pregnancy or while breastfeeding?
Meclizine with Pyridoxine is Pregnancy Category B. Large-scale human studies have not shown any harmful effects on the baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Mecliz Plus?
Symptoms: extreme excitability, seizures, drowsiness and hallucinations. Treatment: appropriate supportive and symptomatic treatment. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Mecliz Plus?
Store Meclizine + Pyridoxine below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Mecliz Plus?
Some medicines can interact with Meclizine + Pyridoxine, for example: Digoxin, Ethanol 70%. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Pyrimac by Advanced Chemical Industries PLC. has the same ingredient and strength for ৳2.50 per unit, compared with ৳3.50 for Mecliz Plus. Ask your doctor or pharmacist before switching.
Do I need a prescription for Mecliz Plus?
Mecliz Plus is a prescription (Rx) medicine. Take it as your doctor advises.