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Same active ingredient — pay up to 33% less
These brands contain the same active ingredient (Montelukast Sodium). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Lotem
Other strengths and forms by Techno Drugs Ltd., Satipara, Narshingdi
Indications & Uses
Lotem is indicated for:
Pharmacology
Montelukast is a selective leukotriene receptor antagonist that works when taken by mouth. It blocks the cysteinyl leukotriene receptor (CysLT1). The cysteinyl leukotrienes (LTC4, LTD4, LTE4) come from the metabolism of arachidonic acid, and various cells release them, including mast cells and eosinophils. Both these leukotrienes and the occupation of their receptors have been linked with the pathophysiology of asthma & allergic rhinitis. This includes airway edema, smooth muscle contraction and altered cellular activity tied to the inflammatory process, and all of these add to the signs and symptoms of asthma.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and adolescents with asthma or seasonal allergic rhinitis: for adults and adolescents 15 years of age and older, the dose is one Montelukast 10 mg tablet once daily.
Children with asthma or seasonal allergic rhinitis: for children 6 to 14 years of age, the dose is one Montelukast 5 mg tablet once daily. For children 2 years to 5 years of age, it is one Montelukast 4 mg tablet once daily. For children 6 months to 5 years of age, the dose is Montelukast 4 mg oral granules once daily. The granules can be given directly in the mouth, or mixed with a spoonful of cold water or soft food at room temperature.
Use in children: the safety and efficacy of Montelukast have been established in adequate and well-controlled studies in children with asthma aged 6 months to 14 years. The safety and efficacy profiles in this age group are similar to those seen in adults.
Hepatic insufficiency: no dosage adjustment is required in patients with mild-to-moderate hepatic insufficiency.
Renal insufficiency: no dosage adjustment is recommended in patients with renal insufficiency.
Elderly use: the pharmacokinetic profile and the oral bioavailability of a single 10-mg oral dose of montelukast are similar in elderly and younger adults. The plasma half-life of montelukast is slightly longer in the elderly. No dosage adjustment is required in the elderly.
Side Effects
Common side effects of Montelukast Sodium are diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions and upper respiratory tract infection. Uncommon ones include akathisia, anxiety, arthralgia, asthenia, abnormal behaviour, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation and sleep disorders. Rare side effects are angioedema, impaired concentration, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies and tremor.
Cautions & Contraindications
Warnings & Precautions
Montelukast Sodium should not be used to reverse bronchospasm during an acute asthma attack, and that includes status asthmaticus. Patients should be told to keep a suitable rescue medicine within reach. The Montelukast Sodium course can carry on through an acute worsening of asthma. The dose of an inhaled corticosteroid may be lowered gradually under medical supervision. But Montelukast Sodium should not be swapped in suddenly for inhaled or oral corticosteroids. It also should not be used alone to treat and manage exercise induced bronchospasm. Patients who are known to be sensitive to aspirin should keep avoiding aspirin and non-steroidal anti-inflammatory agents while they take Montelukast Sodium. The medicine does improve airway function in asthmatics with documented aspirin sensitivity. Even so, it has not been shown to shorten the bronchoconstrictor response to aspirin and other non-steroidal anti-inflammatory drugs in aspirin-sensitive asthmatic patients.
Contraindications
Don't give Montelukast to anyone who is allergic to it or to any other ingredient in the product.
Pregnancy & Breastfeeding
Montelukast has been shown to cross the placenta in rats and rabbits after oral dosing. There are no adequate and well-controlled studies in pregnant women, though. Animal reproduction studies don't always predict how humans will respond, so Montelukast should be used during pregnancy only if it is clearly needed. Many drugs pass into human milk, so a nursing mother should be given Montelukast with caution.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Most overdose reports with Montelukast Sodium described no adverse experiences at all. Where they did occur, the most common ones matched the known safety profile of the medicine and included abdominal pain, somnolence, thirst, headache, vomiting and psychomotor hyperactivity. If an overdose happens, the usual supportive measures are reasonable, for example removing any unabsorbed material from the gastrointestinal tract, clinical monitoring, and supportive therapy if it is required.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Montelukast Sodium in a cool, dry place where the temperature stays below 30°C. Protect it from light and moisture. Keep it out of reach of children.
Drug Interactions
Common questions about Lotem 10 mg
What is Lotem 10 mg Tablet?
Lotem 10 mg Tablet is a medicine that contains Montelukast Sodium. It is made by Techno Drugs Ltd., Satipara, Narshingdi. It belongs to the Leukotriene receptor antagonists group of medicines.
What is Lotem used for?
Lotem is used for: Asthma, Allergic Rhinitis.
What are the side effects of Lotem?
Common side effects of Montelukast Sodium are diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions and upper respiratory tract infection. Uncommon ones include akathisia, anxiety, arthralgia, asthenia, abnormal behaviour, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation and sleep disorders.
Can I take Lotem during pregnancy or while breastfeeding?
Montelukast has been shown to cross the placenta in rats and rabbits after oral dosing. There are no adequate and well-controlled studies in pregnant women, though. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Lotem?
Most overdose reports with Montelukast Sodium described no adverse experiences at all. Where they did occur, the most common ones matched the known safety profile of the medicine and included abdominal pain, somnolence, thirst, headache, vomiting and psychomotor hyperactivity. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Lotem?
Keep Montelukast Sodium in a cool, dry place where the temperature stays below 30°C. Protect it from light and moisture.
Can I take other medicines with Lotem?
Some medicines can interact with Montelukast Sodium, for example: Prednisolone, Theophylline, Digoxin, Terfenadine, Estradiol, Phenobarbital. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
G-Montelukast by Gonoshasthaya Pharmaceuticals Ltd. has the same ingredient and strength for ৳10.00 per unit, compared with ৳15.00 for Lotem. Ask your doctor or pharmacist before switching.
Do I need a prescription for Lotem?
Lotem is a prescription (Rx) medicine. Take it as your doctor advises.