Pricing
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All price changes →Lodin Plus
Rx10 mg+240 mg • Tablet (Extended Release)
Indications & Uses
Lodin Plus is indicated for:
Pharmacology
Loratadine is a long acting tricyclic anti-histamine that blocks histamine H1-receptors. It has anti-allergic properties and does not cause sedation. Its action is selective for the peripheral H1-receptors, and it has no central sedative or anti-cholinergic effect.
Pseudoephedrine is an orally active sympathomimetic amine. It acts as a decongestant on the nasal mucosa and is recognized as an effective agent for relieving nasal congestion due to allergic rhinitis. It has both nasal and bronchial decongestant activity. Pseudoephedrine is an α- and β-adrenergic receptor agonist. By directly stimulating the α-adrenergic receptors of the respiratory mucosa, it causes vasoconstriction. It also directly stimulates β-adrenergic receptors, which causes bronchial relaxation and an increase in heart rate and contractility.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and children over 12 years can take the 5/120 tablet as one tablet twice daily, every 12 hours. The 10/240 tablet is one tablet once daily, and it should be taken in the morning rather than at night.
People with renal insufficiency (GFR<30 ml/min) should start on a lower dose, which is one 5/120 tablet per day or one 10/240 tablet every alternate day. This is because their bodies clear Loratadine and Pseudoephedrine more slowly.
The 10/240 tablet should not be used by anyone with a history of difficulty in swallowing tablets, known narrowing of the upper gastrointestinal tract, or abnormal esophageal peristalsis.
Paediatric use: Safety and effectiveness in children below the age of 12 years have not been established.
Use in patients approximately 60 years of age and older: The safety and efficacy of this tablet in patients older than 60 years have not been investigated in placebo-controlled clinical trials. Elderly people are more likely to have adverse reactions to sympathomimetic amines.
Side Effects
Loratadine + Pseudoephedrine is generally well tolerated. Clinical trials suggest that side effects are very uncommon. The ones reported most often are dry mouth, somnolence, insomnia, pharyngitis, dizziness, coughing, fatigue, nausea, nervousness, anorexia, dysmenorrhoea and headache. Less common side effects may include increased sweating, thirst, back pain, chest pain, malaise, palpitations, hypertension, tachycardia, abdominal distension, altered taste, flatulence, myalgia, dry throat, agitation, frequent urination and so on.
Cautions & Contraindications
Warnings & Precautions
Loratadine + Pseudoephedrine tablets should generally be avoided in patients with hepatic insufficiency. Patients with renal insufficiency should start on a lower dose, because their bodies clear Loratadine and Pseudoephedrine more slowly. The reason is that the doses of this fixed combination product can't be adjusted individually for each ingredient, and hepatic insufficiency reduces the clearance of Loratadine to a much greater extent than that of Pseudoephedrine. Use the tablet with caution in patients with hypertension, diabetes mellitus, ischemic heart disease, increased intraocular pressure, hyperthyroidism or renal impairment. Caution is also needed where hypotension may be produced by sympathomimetic amines.
Contraindications
Don't give this loratadine and pseudoephedrine tablet to anyone who is hypersensitive to any of its components.
Pregnancy & Breastfeeding
Loratadine + Pseudoephedrine falls under pregnancy category B, and no evidence of risk in humans has been reported. It isn't known whether this combination product passes into human milk. But loratadine and pseudoephedrine both pass into breast milk when given alone, so the combination should not be given to breastfeeding mothers.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
If someone takes too much Loratadine + Pseudoephedrine, general symptomatic and supportive measures should be started promptly and kept up for as long as necessary. Treatment would reasonably begin with emesis using ipecac syrup, except in patients with impaired consciousness. Activated charcoal is then given to absorb any drug that remains. If vomiting doesn't work or can't be used, gastric lavage should be done with normal saline.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Loratadine + Pseudoephedrine in a cool, dry place, away from light. Keep it out of the reach of children.
Drug Interactions
Common questions about Lodin Plus 10 mg+240 mg
What is Lodin Plus 10 mg+240 mg Tablet (Extended Release)?
Lodin Plus 10 mg+240 mg Tablet (Extended Release) is a medicine that contains Loratadine + Pseudoephedrine. It is made by Amico Laboratories Ltd. It belongs to the Anti-histamine & decongestant group of medicines.
What is Lodin Plus used for?
Lodin Plus is used for: Allergic Rhinitis, Fever, Urticaria.
What are the side effects of Lodin Plus?
Loratadine + Pseudoephedrine is generally well tolerated. Clinical trials suggest that side effects are very uncommon.
Can I take Lodin Plus during pregnancy or while breastfeeding?
Loratadine + Pseudoephedrine falls under pregnancy category B, and no evidence of risk in humans has been reported. It isn't known whether this combination product passes into human milk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Lodin Plus?
If someone takes too much Loratadine + Pseudoephedrine, general symptomatic and supportive measures should be started promptly and kept up for as long as necessary. Treatment would reasonably begin with emesis using ipecac syrup, except in patients with impaired consciousness. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Lodin Plus?
Keep Loratadine + Pseudoephedrine in a cool, dry place, away from light. Keep it out of the reach of children.
Can I take other medicines with Lodin Plus?
Some medicines can interact with Loratadine + Pseudoephedrine, for example: Erythromycin, Methyldopa, Cimetidine, Ketoconazole, Loratadine. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Lodin Plus is already among the lowest-priced brands of Loratadine + Pseudoephedrine at this strength.
Do I need a prescription for Lodin Plus?
Lodin Plus is a prescription (Rx) medicine. Take it as your doctor advises.