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Other brands with the same active ingredient
These brands contain the same active ingredient (Clindamycin). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Lincocin
Other strengths and forms by The ACME Laboratories Ltd.
Indications & Uses
Lincocin is indicated for:
Pharmacology
Clindamycin phosphate is a water-soluble ester derived from the parent antibiotic lincomycin. It works by inhibiting bacterial protein synthesis, binding preferentially to the 50S ribosomal subunit and interfering with peptide chain initiation. In laboratory (in vitro) testing, clindamycin has shown activity against most strains of the following organisms known to be associated with bacterial vaginosis: *Bacteroides* species, *Gardnerella vaginalis*, *Mobiluncus* species, *Mycoplasma hominis*, and *Peptostreptococcus* species.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Clindamycin capsule dosage for adults
For serious infections, the adult dose is 150 mg to 300 mg every six hours. For more severe infections, it is 300 mg to 450 mg every six hours. Clindacin capsules should be taken with a full glass of water, which lowers the chance of irritation of the oesophagus.
Several studies have found that a Clindamycin 300 mg capsule keeps the plasma concentration above the MIC90 for more than 12 hours. This supports twice-daily dosing of the Clindacin 300 mg capsule, particularly in SSTIs and RTIs. For bone and joint infections and diabetic foot infections, though, the dose of Clindamycin should be one 300 mg capsule 3 to 4 times daily.
Clindamycin IV/IM injection for adults
For serious infections caused by aerobic gram-positive cocci and the more susceptible anaerobes, the dose is 600 to 1200 mg a day, given in 2 to 4 equal doses. For more severe infections, it is 1200 to 2700 mg a day in 2 to 4 equal doses.
In more serious infections these doses may have to be increased. The same applies in life-threatening situations caused by either aerobes or anaerobes. Doses of as much as 4800 mg daily have been given intravenously to adults. A single intramuscular injection of more than 600 mg is not recommended.
Treatment can be changed from the injection to Clindamycin hydrochloride capsules when the condition allows, at the doctor's discretion. For (3-hemolytic streptococcal infections, treatment should continue for at least 10 days.
Side Effects
Adverse effects reported with Clincin include abdominal pain, oesophagitis and oesophageal ulcer, nausea, vomiting, and diarrhoea, as well as itching, skin rashes, and urticaria (hives).
Cautions & Contraindications
Warnings & Precautions
Clindamycin should be used cautiously in people with a history of stomach or bowel problems, especially colitis.
Contraindications
Clindamycin should not be used by anyone who has previously had an allergic or sensitivity reaction to clindamycin itself or to any of the other ingredients in this medicine.
Pregnancy & Breastfeeding
Pregnancy Category B. Studies show that clindamycin does cross the placenta in humans; after several doses, levels in the amniotic fluid reach roughly 30% of the mother's blood concentration. Because of this, clindamycin should only be used during pregnancy when it is genuinely needed. The medicine is also known to pass into breast milk, so it is best avoided by breastfeeding mothers unless there is a clear need for it.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Use in newborns and infants
When Clindamycin is given to newborns and infants (from birth to 16 years), it is desirable to monitor how the organ systems are working.
Geriatric use
Clindamycin doesn't need a dose adjustment in older people.
Overdose
Overdose of oral Clindamycin has rarely been reported. The adverse reactions are likely to be the same as those seen at normal doses, but unexpected reactions could still occur. Haemodialysis and peritoneal dialysis don't remove Clindamycin from the serum. Simple gastric lavage is the treatment for overdose, and no specific antidote is known.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Clindamycin below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Lincocin 300 mg
What is Lincocin 300 mg Capsule?
Lincocin 300 mg Capsule is a medicine that contains Clindamycin. It is made by The ACME Laboratories Ltd. It belongs to the Macrolides group of medicines.
What is Lincocin used for?
Lincocin is used for: Skin and Soft Tissue Infection, Sepsis.
What are the side effects of Lincocin?
Adverse effects reported with Clincin include abdominal pain, oesophagitis and oesophageal ulcer, nausea, vomiting, and diarrhoea, as well as itching, skin rashes, and urticaria (hives).
Can I take Lincocin during pregnancy or while breastfeeding?
Pregnancy Category B. Studies show that clindamycin does cross the placenta in humans; after several doses, levels in the amniotic fluid reach roughly 30% of the mother's blood concentration. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Lincocin?
Overdose of oral Clindamycin has rarely been reported. The adverse reactions are likely to be the same as those seen at normal doses, but unexpected reactions could still occur. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Lincocin?
Store Clindamycin below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Lincocin?
Some medicines can interact with Clindamycin, for example: Erythromycin, Doxophylline, Clindamycin + Tretinoin, Chloramphenicol, Cisatracurium Besylate. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Anobac by Globe Pharmaceuticals Ltd. has the same ingredient and strength for ৳15.00 per unit, compared with ৳15.04 for Lincocin. Ask your doctor or pharmacist before switching.
Do I need a prescription for Lincocin?
Lincocin is a prescription (Rx) medicine. Take it as your doctor advises.